A0A2K6AIU9 · A0A2K6AIU9_MANLE

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentbasolateral part of cell
Cellular Componentbasolateral plasma membrane
Cellular Componentciliary base
Cellular Componentcytoplasmic vesicle membrane
Cellular Componentearly endosome
Cellular Componentendoplasmic reticulum
Cellular Componentlate endosome
Cellular Componentlateral plasma membrane
Cellular Componentlumenal side of membrane
Cellular Componentlysosome
Cellular Componentmembrane raft
Cellular Componentneuron projection
Cellular Componentneuronal cell body
Cellular Componenttransport vesicle
Cellular Componentvoltage-gated potassium channel complex
Molecular Functioncalmodulin binding
Molecular Functiondelayed rectifier potassium channel activity
Molecular Functionoutward rectifier potassium channel activity
Molecular Functionphosphatidylinositol-4,5-bisphosphate binding
Molecular Functionprotein kinase A catalytic subunit binding
Molecular Functionprotein kinase A regulatory subunit binding
Molecular Functionprotein phosphatase 1 binding
Molecular Functionscaffold protein binding
Molecular Functiontransmembrane transporter binding
Molecular Functionvoltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
Molecular Functionvoltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
Biological Processadrenergic receptor signaling pathway
Biological Processauditory receptor cell development
Biological Processcellular response to cAMP
Biological Processcellular response to epinephrine stimulus
Biological Processcellular response to xenobiotic stimulus
Biological Processcochlea development
Biological Processcorticosterone secretion
Biological Processdetection of mechanical stimulus involved in sensory perception of sound
Biological Processerythrocyte differentiation
Biological Processgastrin-induced gastric acid secretion
Biological Processglucose metabolic process
Biological Processheart development
Biological Processinner ear morphogenesis
Biological Processintracellular chloride ion homeostasis
Biological Processiodide transport
Biological Processmembrane repolarization during atrial cardiac muscle cell action potential
Biological Processnon-motile cilium assembly
Biological Processpositive regulation of cardiac muscle contraction
Biological Processpositive regulation of heart rate
Biological Processpositive regulation of potassium ion transmembrane transport
Biological Processpotassium ion export across plasma membrane
Biological Processpotassium ion homeostasis
Biological Processpotassium ion import across plasma membrane
Biological Processregulation of atrial cardiac muscle cell membrane repolarization
Biological Processregulation of blood pressure
Biological Processregulation of gastric acid secretion
Biological Processregulation of heart rate by cardiac conduction
Biological Processregulation of ventricular cardiac muscle cell membrane repolarization
Biological Processrenal sodium ion absorption
Biological Processresponse to insulin
Biological Processrhythmic behavior
Biological Processsocial behavior
Biological Processstomach development

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Potassium voltage-gated channel subfamily KQT member 1
  • Alternative names
    • IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1
    • KQT-like 1
    • Voltage-gated potassium channel subunit Kv7.1

Gene names

    • Name
      KCNQ1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Mandrillus

Accessions

  • Primary accession
    A0A2K6AIU9

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane39-58Helical
Transmembrane64-89Helical
Transmembrane116-139Helical
Transmembrane178-200Helical
Transmembrane212-231Helical
Transmembrane243-269Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain40-274Ion transport
Domain421-533Potassium channel voltage dependent KCNQ C-terminal
Region535-592Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    592
  • Mass (Da)
    66,502
  • Last updated
    2018-03-28 v1
  • Checksum
    B77D09388F8D8720
VNLDPRVSIYSTRRPLLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSSTWKIYVRKPSRSHTLLSSSPKPKKSVVVKKKKFKLDKDNGVSPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSTPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSPPGSGGPPREGGVHVTQPCGSGGSVDPELFLPSNALPTYEQLTVPRRGPDEGS

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A2K6AIU5A0A2K6AIU5_MANLEKCNQ1549

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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