A0A2K5LJC2 · A0A2K5LJC2_CERAT

Function

Features

Showing features for binding site.

160350100150200250300350400450500550600
TypeIDPosition(s)Description
Binding site77-80a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) (UniProtKB | ChEBI)
Binding site295a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentactin filament
Cellular Componentapical plasma membrane
Cellular Componentcell cortex
Cellular Componentcytosol
Cellular Componentendosome
Cellular Componentfibrillar center
Cellular Componentfilopodium
Cellular Componentfocal adhesion
Cellular Componentimmunological synapse
Cellular Componentmicrovillus membrane
Cellular Componentperinuclear region of cytoplasm
Cellular Componentplasma membrane raft
Cellular Componentprotein-containing complex
Cellular Componentruffle membrane
Molecular Functionactin filament binding
Molecular FunctionATPase binding
Molecular Functioncell adhesion molecule binding
Molecular Functionidentical protein binding
Molecular Functionmicrotubule binding
Molecular Functionprotein domain specific binding
Molecular Functionprotein kinase A catalytic subunit binding
Molecular Functionprotein kinase A regulatory subunit binding
Molecular FunctionS100 protein binding
Biological Processactin filament bundle assembly
Biological Processastral microtubule organization
Biological Processcellular response to cAMP
Biological Processcortical microtubule organization
Biological Processestablishment of centrosome localization
Biological Processestablishment of endothelial barrier
Biological Processfilopodium assembly
Biological Processleukocyte cell-cell adhesion
Biological Processmembrane to membrane docking
Biological Processmicrovillus assembly
Biological Processnegative regulation of ERK1 and ERK2 cascade
Biological Processnegative regulation of interleukin-2 production
Biological Processnegative regulation of p38MAPK cascade
Biological Processnegative regulation of T cell receptor signaling pathway
Biological Processnegative regulation of transcription by RNA polymerase II
Biological Processpositive regulation of early endosome to late endosome transport
Biological Processpositive regulation of gene expression
Biological Processpositive regulation of protein catabolic process
Biological Processpositive regulation of protein localization to early endosome
Biological Processprotein kinase A signaling
Biological Processprotein localization to cell cortex
Biological Processprotein localization to plasma membrane
Biological Processprotein-containing complex localization
Biological Processregulation of cell shape
Biological Processregulation of organelle assembly
Biological Processsphingosine-1-phosphate receptor signaling pathway

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Ezrin
  • Alternative names
    • Cytovillin
    • Villin-2
    • p81

Gene names

    • Name
      EZR

Organism names

Accessions

  • Primary accession
    A0A2K5LJC2

Proteomes

Subcellular Location

Apical cell membrane
; Peripheral membrane protein
Cell projection, microvillus membrane
; Peripheral membrane protein
Cell projection, ruffle membrane
; Peripheral membrane protein
Cytoplasm, cell cortex
Cytoplasm, cytoskeleton
Membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain22-312FERM
Region323-358Disordered
Region502-579Disordered
Compositional bias522-544Basic and acidic residues
Compositional bias557-579Basic and acidic residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    603
  • Mass (Da)
    71,452
  • Last updated
    2018-03-28 v1
  • Checksum
    D934729C24AB480B
LPPRFKHFSCLSLPSSWDYVQINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLQYVDNKGFPTWLKLDKKVSAQEVRKENPLQFKFRAKFFPEDVAEELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWHAEHRGMLKDNAMLEYLKIAQDLEMYGINYFEIKNKKGTELWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPLSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQRQLLTLSSELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAL

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A2K5LJH2A0A2K5LJH2_CERATEZR588
A0A2K5LJA5A0A2K5LJA5_CERATEZR586
A0A2K5LJF5A0A2K5LJF5_CERATEZR565

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias522-544Basic and acidic residues
Compositional bias557-579Basic and acidic residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp