A0A2K5I6P1 · A0A2K5I6P1_COLAP

Function

function

Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionL-methionine-(R)-S-oxide reductase activity
Molecular Functionmetal ion binding
Molecular Functionpeptide-methionine (R)-S-oxide reductase activity
Biological Processprotein repair
Biological Processresponse to oxidative stress

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Peptide-methionine (R)-S-oxide reductase
  • EC number

Organism names

Accessions

  • Primary accession
    A0A2K5I6P1

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-26
ChainPRO_501579778627-188Peptide-methionine (R)-S-oxide reductase

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain43-165MsrB
Region165-188Disordered

Sequence similarities

Belongs to the MsrB Met sulfoxide reductase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    188
  • Mass (Da)
    20,243
  • Last updated
    2018-03-28 v1
  • MD5 Checksum
    36DD66A017983DFD1FD9CD0469D032BA
MSPRRTLPRPLSLCLCLCLAAALGSAQSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGTESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSFHDVITSEAITFTDDFSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGAAEGGSGVASPAQADKAEL

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A2K5I6P0A0A2K5I6P0_COLAP185
A0A2K5I6Q1A0A2K5I6Q1_COLAP156

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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