A0A2K5HEW5 · A0A2K5HEW5_COLAP

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

  • Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.
    EC:3.4.21.6 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

148850100150200250300350400450
TypeIDPosition(s)Description
Active site276Charge relay system
Active site322Charge relay system
Active site419Charge relay system

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum lumen
Cellular Componentextracellular space
Cellular ComponentGolgi lumen
Molecular Functioncalcium ion binding
Molecular Functionserine-type endopeptidase activity
Biological Processblood coagulation
Biological Processpositive regulation of leukocyte chemotaxis
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Coagulation factor X
  • EC number
  • Alternative names
    • Stuart factor

Organism names

Accessions

  • Primary accession
    A0A2K5HEW5

Proteomes

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-23
ChainPRO_501438637524-488Coagulation factor X
Disulfide bond112↔121

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain40-86Gla
Domain86-122EGF-like
Domain235-467Peptidase S1

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    488
  • Mass (Da)
    54,766
  • Last updated
    2018-03-28 v1
  • Checksum
    DEF17E8B1086A4C6
MGRPLHLVLLSASLASLLLPGESLFIRREQASNVLARVRRSNSFLEEIKKGNLERECMEEICSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNEGECRDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATNSSGEAPDSIPWKPEDAADLDATENPFDLLDFNQTQPERGDNNLIRIVGGRECKNGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRDTEQEEGGEAVHEVEVIIKHNRFTKETYDFDIAVLRLKSPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYHAKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAESRAPEVSTSSPLK

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

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