A0A2K3CUX5 · A0A2K3CUX5_CHLRE
- ProteinMethionine synthase reductase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1772 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Cofactor
Protein has several cofactor binding sites:
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | [methionine synthase] reductase activity | |
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | FMN binding | |
Biological Process | homocysteine metabolic process | |
Biological Process | methionine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethionine synthase reductase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Chlorophyta > core chlorophytes > Chlorophyceae > CS clade > Chlamydomonadales > Chlamydomonadaceae > Chlamydomonas
Accessions
- Primary accessionA0A2K3CUX5
Proteomes
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-29 | |||||
Sequence: MKIGVAVAGGFGALLLLTPLATFLLAASA | ||||||
Chain | PRO_5014446734 | 30-1772 | Methionine synthase reductase | |||
Sequence: QKRKTSPKGGDKAARKSETKESNDKAVPMNAGNAAPPSARAVAAAPAAAAATGGNAILARLKQQRAAPPPPAVAATAGAKPPLTFAFASQTGTGAEIARNLAAEAVEKGYKAQCMSLTELGYAALTSGRTPYLVIVASSTGDGDPPDNSGAFFVALRKKQEGKPLVGVKFTLLGLGDSNYTRFMYVSRAIKGRLLDLGAAEFYPCAEADEVDGIESVVDPWSEGLWTALAAETPAAAEQQPPAEVAAAAPAAAPVAAVSVAAPSASVPAPSTGATSSAATGGNAILARLRQQRAAPMEGGAATAAIEPSTTAAAASSAPAAAVAEAGVVVHVATAAAPPGKQDAATAAAPAPAAAAATGGNAILARLKQQRAAPPPPAVAATAGTKPPLTFAFASQTGTGAEIARNLAAEAVEKGYKAQCMSLTELGYAALTSGRTPYLVIVASSTGDGDPPDNSGAFFVALRKKQEGKPLVGVKFTLLGLGDSNYTRFMYVSRAIKGRLLDLGAAEFYPCAEADEVDGIESVVDPWSEGLWTALDADIAPQKDQAADQPPVAVTAGPSGPSRRSVEMMTGMSRTPAASAMPSKPSTPGPQTPTTPGTPSAVAATAPALVDAPSRSLVPETSAKSAVPKVEEAAVPVAATGGAAVLAKLRSGQPNADSAESLTVAAAAAAPEAAAKQENTAAKSAQPPAEPAKPPVTFAYASQTGTGEEIARNLAAEAIQRGYKAICAPLNELGFAAITPSRTPVLVVIASSTGDGDPPENATNFFVALRKKQDKPAPLAGVRYTLLGLGDSNYTRFMGAPRAIKSRLAELGAAEFYPCAEADEVDGIESVVDRWTAGIWAAIAAATAAGQDAMAAVSIDAPSATAAVKPAAVKVGPSESEIAAAAAAAAVAAEAAAKAAAEKEAAEKAAKEPAEKAATEAAEKEAAETAAKEAAEAAEKAAKEAAEKEAAEQAAKDAAEKEAAEKETAEKAAKEAAEKEAAEKEAAEQEAAEKAAKEAAEKEAAEKAAAEKAAKEAADMVAAEAATRAGAEATTAEEAATAATVSAAADAEELAEAEASAAALAAAAQHPERPSSTATSDDGGSLLPSSLLSVMEAGAAPGAHDHGLPTIKESRVFEEEPEPEAAAEAGAKEGKPSGLKVLPEAATEDGDDPLLSPRETEDGGDDMLLTPRGSVRGGGGRPDSRGSVASSTATGTTGTWRRSVDLKSKSHMVAEAARRRSLEKPARLQAKPLNVNFPKREENVVKRKDEKAYGLLLGLAPVGVDTKGAPALLPCRLRLLWEKDEKRTDGVLTREMLRPSREERHKLDPGGMYSPQQPFWAHISDARYETAFWSDRKVLHLELSIRGSNIAYSPGDAIGVLPANHPDLVANLCKRLNLNADRVFYISAPKDTSQAGDAASEAGEAAPATPAGRPATHIPSPCSIGYAFANCVDLTSPARKSLLRLLAEHAHDASEKRTLLFLSAKGGKDAYAHEIAEHQPSLLDLLVRFPSVTPPLDALLDALPPLAPRMYSITSSRRDSAKGPNRLSVALSVVRFKTRYGTRLGVASAWLDRLASPWTTEGISNPANPVWVPIYLRRSADFKPPADLSSPLIMVGPGTGVAPFRGFLQERRALIRENKPESVGEAVLFFGCRREDEDYIFKEELELMKAEGTLSALHVAFSRAQETKVYVQDLIKAQGEKVWGLLQAGGYLYVCGDGAAMAKDVHAALIAVAGTHGGLSEADATAFLQNLTRERRYVRDVWS |
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 29-63 | Disordered | ||||
Sequence: AQKRKTSPKGGDKAARKSETKESNDKAVPMNAGNA | ||||||
Compositional bias | 34-52 | Basic and acidic residues | ||||
Sequence: TSPKGGDKAARKSETKESN | ||||||
Domain | 112-255 | Flavodoxin-like | ||||
Sequence: LTFAFASQTGTGAEIARNLAAEAVEKGYKAQCMSLTELGYAALTSGRTPYLVIVASSTGDGDPPDNSGAFFVALRKKQEGKPLVGVKFTLLGLGDSNYTRFMYVSRAIKGRLLDLGAAEFYPCAEADEVDGIESVVDPWSEGLW | ||||||
Domain | 418-561 | Flavodoxin-like | ||||
Sequence: LTFAFASQTGTGAEIARNLAAEAVEKGYKAQCMSLTELGYAALTSGRTPYLVIVASSTGDGDPPDNSGAFFVALRKKQEGKPLVGVKFTLLGLGDSNYTRFMYVSRAIKGRLLDLGAAEFYPCAEADEVDGIESVVDPWSEGLW | ||||||
Region | 572-631 | Disordered | ||||
Sequence: KDQAADQPPVAVTAGPSGPSRRSVEMMTGMSRTPAASAMPSKPSTPGPQTPTTPGTPSAV | ||||||
Region | 704-724 | Disordered | ||||
Sequence: AKQENTAAKSAQPPAEPAKPP | ||||||
Domain | 725-869 | Flavodoxin-like | ||||
Sequence: VTFAYASQTGTGEEIARNLAAEAIQRGYKAICAPLNELGFAAITPSRTPVLVVIASSTGDGDPPENATNFFVALRKKQDKPAPLAGVRYTLLGLGDSNYTRFMGAPRAIKSRLAELGAAEFYPCAEADEVDGIESVVDRWTAGIW | ||||||
Compositional bias | 933-1047 | Basic and acidic residues | ||||
Sequence: EAAEKAAKEPAEKAATEAAEKEAAETAAKEAAEAAEKAAKEAAEKEAAEQAAKDAAEKEAAEKETAEKAAKEAAEKEAAEKEAAEQEAAEKAAKEAAEKEAAEKAAAEKAAKEAA | ||||||
Region | 933-1234 | Disordered | ||||
Sequence: EAAEKAAKEPAEKAATEAAEKEAAETAAKEAAEAAEKAAKEAAEKEAAEQAAKDAAEKEAAEKETAEKAAKEAAEKEAAEKEAAEQEAAEKAAKEAAEKEAAEKAAAEKAAKEAADMVAAEAATRAGAEATTAEEAATAATVSAAADAEELAEAEASAAALAAAAQHPERPSSTATSDDGGSLLPSSLLSVMEAGAAPGAHDHGLPTIKESRVFEEEPEPEAAAEAGAKEGKPSGLKVLPEAATEDGDDPLLSPRETEDGGDDMLLTPRGSVRGGGGRPDSRGSVASSTATGTTGTWRRSVD | ||||||
Compositional bias | 1101-1116 | Polar residues | ||||
Sequence: ERPSSTATSDDGGSLL | ||||||
Compositional bias | 1137-1158 | Basic and acidic residues | ||||
Sequence: LPTIKESRVFEEEPEPEAAAEA | ||||||
Compositional bias | 1174-1195 | Basic and acidic residues | ||||
Sequence: AATEDGDDPLLSPRETEDGGDD | ||||||
Compositional bias | 1214-1232 | Polar residues | ||||
Sequence: RGSVASSTATGTTGTWRRS | ||||||
Domain | 1345-1614 | FAD-binding FR-type | ||||
Sequence: QQPFWAHISDARYETAFWSDRKVLHLELSIRGSNIAYSPGDAIGVLPANHPDLVANLCKRLNLNADRVFYISAPKDTSQAGDAASEAGEAAPATPAGRPATHIPSPCSIGYAFANCVDLTSPARKSLLRLLAEHAHDASEKRTLLFLSAKGGKDAYAHEIAEHQPSLLDLLVRFPSVTPPLDALLDALPPLAPRMYSITSSRRDSAKGPNRLSVALSVVRFKTRYGTRLGVASAWLDRLASPWTTEGISNPANPVWVPIYLRRSADFKPP | ||||||
Region | 1424-1443 | Disordered | ||||
Sequence: AGDAASEAGEAAPATPAGRP |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,772
- Mass (Da)182,052
- Last updated2018-03-28 v1
- ChecksumD9FCCFA024F26FDC
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 34-52 | Basic and acidic residues | ||||
Sequence: TSPKGGDKAARKSETKESN | ||||||
Compositional bias | 933-1047 | Basic and acidic residues | ||||
Sequence: EAAEKAAKEPAEKAATEAAEKEAAETAAKEAAEAAEKAAKEAAEKEAAEQAAKDAAEKEAAEKETAEKAAKEAAEKEAAEKEAAEQEAAEKAAKEAAEKEAAEKAAAEKAAKEAA | ||||||
Compositional bias | 1101-1116 | Polar residues | ||||
Sequence: ERPSSTATSDDGGSLL | ||||||
Compositional bias | 1137-1158 | Basic and acidic residues | ||||
Sequence: LPTIKESRVFEEEPEPEAAAEA | ||||||
Compositional bias | 1174-1195 | Basic and acidic residues | ||||
Sequence: AATEDGDDPLLSPRETEDGGDD | ||||||
Compositional bias | 1214-1232 | Polar residues | ||||
Sequence: RGSVASSTATGTTGTWRRS |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CM008977 EMBL· GenBank· DDBJ | PNW72074.1 EMBL· GenBank· DDBJ | Genomic DNA |