A0A2K2H9A0 · A0A2K2H9A0_9BACT

Function

function

General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site201Tele-phosphohistidine intermediate
Binding site308phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site344phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site443Mg2+ (UniProtKB | ChEBI)
Binding site466-467phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site467Mg2+ (UniProtKB | ChEBI)
Binding site477phosphoenolpyruvate (UniProtKB | ChEBI)
Active site514Proton donor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentmembrane
Molecular Functionkinase activity
Molecular Functionmetal ion binding
Molecular Functionphosphoenolpyruvate-protein phosphotransferase activity
Biological Processphosphoenolpyruvate-dependent sugar phosphotransferase system

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoenolpyruvate-protein phosphotransferase
  • EC number
  • Alternative names
    • Phosphotransferase system, enzyme I

Gene names

    • Name
      ptsP
    • ORF names
      C2E25_10690

Organism names

  • Taxonomic identifier
  • Strain
    • HR-1
  • Taxonomic lineage
    Bacteria > Thermodesulfobacteriota > Desulfuromonadia > Desulfuromonadales > Geothermobacteraceae > Geothermobacter

Accessions

  • Primary accession
    A0A2K2H9A0

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-32Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain16-138Phosphotransferase system enzyme I N-terminal
Domain165-237PEP-utilising enzyme mobile
Domain268-553PEP-utilising enzyme C-terminal

Sequence similarities

Belongs to the PEP-utilizing enzyme family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    594
  • Mass (Da)
    65,965
  • Last updated
    2018-03-28 v1
  • Checksum
    F7259FC7EE560C97
MASVKTEISPDTFLVGIGVSPGIAIGATHLVNRARMAALERRIRKSDVDVEIAAFEEAVELSRRQLHEVKRRVADRHLAEHLYIIDTHLLILEDQMLHAETRRGIREDLLNAEGALKRALDQFRSVFESIEDEYLRDRGSDVESVGERLLRNLMGESEQSLSGIDRKVVVVAHDLSPADTMQIDKDKIIGFVTDVGGRTSHTAILARSQGIPAVVGLENATALIPGGTPLIVDGSSGTVILNPTPETFREYLQKKQRYEYGERELLSYRSLPAETPDGHRLVLRCNVELPSEVPHALAQGAEGVGLFRSEFLYLGRQFPPDEEEQFDAYREIVTAMAPHEVTIRTLDVGGDKFVPEINLSDEVNPALGLRGVRFSLADRQLLKIQLRAILRVSALGPVRVMFPMISGVSEIRACKSILHQAMAELSREGIDFDGRIPVGIMIETPSAALIADKLAREVDFFSVGTNDLIQYCLAVDRSNEHVAYLYEPLHPAILRALQMICRAARQAGIKVAMCGEMAAEPLYLPILIGFGFGELSMNAPCIPRVKRVVRQIRYSEGKELLEKLLQLSTVAEVTHCLEEEMMTRIPDLFGKTDI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PPFX01000023
EMBL· GenBank· DDBJ
PNU19809.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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