A0A2K2H769 · A0A2K2H769_9BACT

Function

function

Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site9-11substrate
Active site95Electrophile
Active site167Proton acceptor
Binding site173substrate
Binding site213substrate
Binding site234-235substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functiontriose-phosphate isomerase activity
Biological Processgluconeogenesis
Biological Processglyceraldehyde-3-phosphate biosynthetic process
Biological Processglycerol catabolic process
Biological Processglycolytic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Triosephosphate isomerase
  • EC number
  • Short names
    TIM
    ; TPI
  • Alternative names
    • Triose-phosphate isomerase

Gene names

    • Name
      tpiA
    • ORF names
      C2E25_13920

Organism names

  • Taxonomic identifier
  • Strain
    • HR-1
  • Taxonomic lineage
    Bacteria > Thermodesulfobacteriota > Desulfuromonadia > Desulfuromonadales > Geothermobacteraceae > Geothermobacter

Accessions

  • Primary accession
    A0A2K2H769

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the triosephosphate isomerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    253
  • Mass (Da)
    26,955
  • Last updated
    2018-03-28 v1
  • Checksum
    49DB64B226765A68
MRRPVIAGNWKMHKTITEAVELAGSLKQAAAGIDHADFIIAPVFTALATVAAELKGSNLKIAGQNCSDQPGGAFTGEVAPQMLLDAGCSHVILGHSERRQLFGENNDLINAKIKAALTAGLRVIFCIGETLEERETGRMYDVLSEQVTQGLAGLSEEQMDRVIVAYEPVWAIGTGKTATSDQAEEAHSFVRGLIAGQFNLQISEQLRILYGGSVKPGNVDELMARDNIDGALVGGASLNADDFIRIMNFSGAN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PPFX01000038
EMBL· GenBank· DDBJ
PNU19166.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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