A0A2K2H6A6 · A0A2K2H6A6_9BACT

Function

function

Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site9-16GTP (UniProtKB | ChEBI)
Binding site34-36GTP (UniProtKB | ChEBI)
Active site50GMP-histidine intermediate
Binding site62GTP (UniProtKB | ChEBI)
Binding site84GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionadenosylcobinamide kinase (ATP-specific) activity
Molecular Functionadenosylcobinamide kinase (GTP-specific) activity
Molecular FunctionATP binding
Molecular Functioncobinamide phosphate guanylyltransferase activity
Molecular FunctionGTP binding
Biological Processcobalamin biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylcobinamide kinase
  • EC number
  • Alternative names
    • Adenosylcobinamide-phosphate guanylyltransferase

Gene names

    • ORF names
      C2E25_15560

Organism names

  • Taxonomic identifier
  • Strain
    • HR-1
  • Taxonomic lineage
    Bacteria > Thermodesulfobacteriota > Desulfuromonadia > Desulfuromonadales > Geothermobacteraceae > Geothermobacter

Accessions

  • Primary accession
    A0A2K2H6A6

Proteomes

Family & Domains

Sequence similarities

Belongs to the CobU/CobP family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    173
  • Mass (Da)
    18,846
  • Last updated
    2018-03-28 v1
  • Checksum
    45CAB3FAC0AAF1C1
MSRLVFITGGARSGKSGYAQRRCEELPGTLLYVATARVEDAEMAERVALHQQQRGERWALLEEPLDLAARLPDVTPGRSAVLLDCLTLWLTNQLFAAGEQPAPVIAAAEQLIETLRRLDIPIFVVSNEVGSGIVPDNALARTFRDLAGRVNQLFAASADEAWLLASGLPLRLK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PPFX01000048
EMBL· GenBank· DDBJ
PNU18855.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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