A0A2K1EFL5 · A0A2K1EFL5_9BACL
- ProteinFluoride-specific ion channel FluC
- GenecrcB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids133 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Catalytic activity
- fluoride(in) = fluoride(out)This reaction proceeds in the forward direction.
Activity regulation
Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | fluoride channel activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular detoxification of fluoride |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameFluoride-specific ion channel FluC
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Paenibacillaceae > Paenibacillus
Accessions
- Primary accessionA0A2K1EFL5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 34-52 | Helical | ||||
Sequence: LGVLLINWIGCLFLGWFFT | ||||||
Transmembrane | 64-84 | Helical | ||||
Sequence: LRLAIGTGFTGGFTTFSTFAV | ||||||
Transmembrane | 96-117 | Helical | ||||
Sequence: LTAVLYLLLSVGGGLFLTWTGI |
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length133
- Mass (Da)14,456
- Last updated2018-03-28 v1
- Checksum32461CBCBA16689C