A0A2J7RBT6 · A0A2J7RBT6_9NEOP
- ProteinTrifunctional purine biosynthetic protein adenosine-3
- GeneGART_3
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1007 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- N1-(5-phospho-beta-D-ribosyl)glycinamide + (6R)-10-formyltetrahydrofolate = N2-formyl-N1-(5-phospho-beta-D-ribosyl)glycinamide + (6S)-5,6,7,8-tetrahydrofolate + H+
Pathway
Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide: step 2/2.
Purine metabolism; IMP biosynthesis via de novo pathway; N1-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.
Purine metabolism; IMP biosynthesis via de novo pathway; N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide from N1-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | phosphoribosylamine-glycine ligase activity | |
Molecular Function | phosphoribosylformylglycinamidine cyclo-ligase activity | |
Molecular Function | phosphoribosylglycinamide formyltransferase activity | |
Biological Process | 'de novo' IMP biosynthetic process | |
Biological Process | adenine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTrifunctional purine biosynthetic protein adenosine-3
Including 3 domains:
- Recommended namePhosphoribosylamine--glycine ligase
- EC number
- Alternative names
- Recommended namePhosphoribosylformylglycinamidine cyclo-ligase
- EC number
- Alternative names
- Recommended namePhosphoribosylglycinamide formyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Polyneoptera > Dictyoptera > Blattodea > Blattoidea > Termitoidae > Kalotermitidae > Cryptotermitinae > Cryptotermes
Accessions
- Primary accessionA0A2J7RBT6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 110-317 | ATP-grasp | |||
Sequence similarities
In the C-terminal section; belongs to the GART family.
In the N-terminal section; belongs to the GARS family.
In the central section; belongs to the AIR synthase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,007
- Mass (Da)106,937
- Last updated2018-03-28 v1
- MD5 Checksum8EE0044FA77A33677DA439755F61AD2F
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
NEVH01005891 EMBL· GenBank· DDBJ | PNF38290.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
NEVH01005891 EMBL· GenBank· DDBJ | PNF38291.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
NEVH01005891 EMBL· GenBank· DDBJ | PNF38292.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
NEVH01005891 EMBL· GenBank· DDBJ | PNF38293.1 EMBL· GenBank· DDBJ | Genomic DNA |