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A0A2J7RBT6 · A0A2J7RBT6_9NEOP

  • Protein
    Trifunctional purine biosynthetic protein adenosine-3
  • Gene
    GART_3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide: step 2/2.
Purine metabolism; IMP biosynthesis via de novo pathway; N1-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.
Purine metabolism; IMP biosynthesis via de novo pathway; N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide from N1-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionphosphoribosylamine-glycine ligase activity
Molecular Functionphosphoribosylformylglycinamidine cyclo-ligase activity
Molecular Functionphosphoribosylglycinamide formyltransferase activity
Biological Process'de novo' IMP biosynthetic process
Biological Processadenine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Trifunctional purine biosynthetic protein adenosine-3

Including 3 domains:

  • Recommended name
    Phosphoribosylamine--glycine ligase
  • EC number
  • Alternative names
    • Glycinamide ribonucleotide synthetase
      (GARS
      )
    • Phosphoribosylglycinamide synthetase
  • Recommended name
    Phosphoribosylformylglycinamidine cyclo-ligase
  • EC number
  • Alternative names
    • AIR synthase
      (AIRS
      )
    • Phosphoribosyl-aminoimidazole synthetase
  • Recommended name
    Phosphoribosylglycinamide formyltransferase
  • EC number
  • Alternative names
    • 5'-phosphoribosylglycinamide transformylase
    • GAR transformylase
      (GART
      )

Gene names

    • Name
      GART_3
    • ORF names
      B7P43_G11608

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Polyneoptera > Dictyoptera > Blattodea > Blattoidea > Termitoidae > Kalotermitidae > Cryptotermitinae > Cryptotermes

Accessions

  • Primary accession
    A0A2J7RBT6

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain110-317ATP-grasp

Sequence similarities

In the C-terminal section; belongs to the GART family.
In the N-terminal section; belongs to the GARS family.
In the central section; belongs to the AIR synthase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,007
  • Mass (Da)
    106,937
  • Last updated
    2018-03-28 v1
  • MD5 Checksum
    8EE0044FA77A33677DA439755F61AD2F
MANVLVIGNGGREHAISWKLAQSEEVKQIYVCPGNAGISQVNKVTCVTLNVKDYEAVASWSKENNISLVVVGPEDPLAGGIADVLRAHGVDCFGPSRAAARIEADKHWAKSFMDRHDIPTARWGAFTSADEAKAFIASASFPALVVKASGLAAGKGVVVASSQSEACNALDSILTDHKFGAAGNTVVVEELLEGEEVSVLAFVDGSNISVMLPSQDHKRHMDGDTGANTGGMGAYCPCPLITESDLAAVTDTILQKAVNGLKMEKSPFIGVLYAGLMLTKDGPKVLEFNCRFGDPETEVVLALLESNLYRIMLACCKGELDNEVLRWRQGAYAVGVVIASRGYPESSSKGNVITGHEVISRWPEHLVFHSGTSVLANGDLVTNGGRVLVVVTIASELMLAAAKATKACGKIVFDGAQYRTDIAHKGIVRSLLQEGRLSYKASGVDIEAGGTLVSRIKRTVELTNRNGVLSSIGGFGGVFDTKAAGYKDPLLVSGTDGVGTKLKIAQACGLHSTVGIDLVAMCVNDILAHGAEPLFFLDYLACGILNVDVASQVVAGVVEGCQEAGCALIGGETAEMPGMYAVGDYDLAGFAVGAVERSRLLPNTEKIQAGDVVIALTSSGVHSNGFSLIRKIVEKYGAQYSDPAPFSESGKSLGEELLTPTKIYVRSLLAALQSGKVKAMAHITGGGLTENIPRILPEGYKVQIDATKWPIPSVFGWLAAAGGISASELLRTFNCGIGAAIIVSALDVEHVLKLITCEVPYTVGTVEARSEGTSQVEVMNFVSAMEALMRPYVNLVMKAHTQNRKRVGVLISGTGTNLQSLIDATLDPSRGTGAEIVLVISNRPKVLGLTRAQKANIPTKVIPHTAYKSRLEFDMAMHSELMAAGIEIVCLAGFMRILTGDFVRLWRGRLINIHPALLPLFKGTHAHRQALEAGVRITGCTAHFVEEDIDSGAILVQESVQIELGDTEETLEERVKQAEHKVFPKALKLVATGKVYLNETGKLVWRQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NEVH01005891
EMBL· GenBank· DDBJ
PNF38290.1
EMBL· GenBank· DDBJ
Genomic DNA
NEVH01005891
EMBL· GenBank· DDBJ
PNF38291.1
EMBL· GenBank· DDBJ
Genomic DNA
NEVH01005891
EMBL· GenBank· DDBJ
PNF38292.1
EMBL· GenBank· DDBJ
Genomic DNA
NEVH01005891
EMBL· GenBank· DDBJ
PNF38293.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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