A0A2I3SKB7 · A0A2I3SKB7_PANTR
- ProteinMultidrug and toxin extrusion protein 1
- GeneSLC47A1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids443 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- H+(in) + thiamine(out) = H+(out) + thiamine(in)
- agmatine(in) + H+(out) = agmatine(out) + H+(in)This reaction proceeds in the forward and the backward directions.
- creatinine(in) + H+(out) = creatinine(out) + H+(in)
- estrone 3-sulfate(in) + H+(out) = estrone 3-sulfate(out) + H+(in)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | apical plasma membrane | |
Molecular Function | antiporter activity | |
Molecular Function | xenobiotic transmembrane transporter activity | |
Biological Process | xenobiotic detoxification by transmembrane export across the plasma membrane |
Names & Taxonomy
Protein names
- Recommended nameMultidrug and toxin extrusion protein 1
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Pan
Accessions
- Primary accessionA0A2I3SKB7
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Apical cell membrane ; Multi-pass membrane protein
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 37-62 | Helical | ||||
Sequence: ALLVLAGPAFLVQLMVFLISFISSVF | ||||||
Transmembrane | 97-121 | Helical | ||||
Sequence: ALVLLLCCFPCWALFLNTQHILLLF | ||||||
Transmembrane | 133-150 | Helical | ||||
Sequence: TYVTIFIPALPATFLYML | ||||||
Transmembrane | 162-182 | Helical | ||||
Sequence: LPQIVTGVAANLVNALANYLF | ||||||
Transmembrane | 194-213 | Helical | ||||
Sequence: ALANLISQYTLALLLFLYIL | ||||||
Transmembrane | 233-253 | Helical | ||||
Sequence: WASFLRLAVPSMLMLCMEWWA | ||||||
Transmembrane | 274-295 | Helical | ||||
Sequence: IVYELAIIVYMVPAGFSVAASV | ||||||
Transmembrane | 315-334 | Helical | ||||
Sequence: VSLLITVLFAVAFSVLLLSC | ||||||
Transmembrane | 355-376 | Helical | ||||
Sequence: VVPIYAVSHLFEALACTSGGVL | ||||||
Transmembrane | 391-413 | Helical | ||||
Sequence: IGYYVVGLPIGIVLMFATTLGVM |
Keywords
- Cellular component
Expression
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length443
- Mass (Da)48,038
- Last updated2018-02-28 v1
- Checksum199ABC210A08E3DC
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A2I3T1C4 | A0A2I3T1C4_PANTR | SLC47A1 | 268 | ||
A0A2I3RKH3 | A0A2I3RKH3_PANTR | SLC47A1 | 570 | ||
A0A2I3SBB7 | A0A2I3SBB7_PANTR | SLC47A1 | 316 | ||
H2RBV0 | H2RBV0_PANTR | SLC47A1 | 586 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AACZ04044787 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |