A0A2I3BQW0 · A0A2I3BQW0_MOUSE
- ProteinASXL transcriptional regulator 1
- GeneAsxl1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1513 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA binding | |
Molecular Function | metal ion binding | |
Biological Process | regulation of DNA-templated transcription |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionA0A2I3BQW0
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 11-85 | HTH HARE-type | ||||
Sequence: RTWAEAARLVLENYSDAPMTPKQILQVIEAEGLKEMSGTSPLACLNAMLHSNSRGGEGLFYKLPGRISLFTLKKD | ||||||
Region | 94-169 | Disordered | ||||
Sequence: ATVDGDEPEDSADVESCGSNEASTVSGENDVSLDETSSNASCSTESQSRPLSNPRDSHRASSQANKQKKRTGVMLP | ||||||
Compositional bias | 109-153 | Polar residues | ||||
Sequence: SCGSNEASTVSGENDVSLDETSSNASCSTESQSRPLSNPRDSHRA | ||||||
Region | 182-248 | Disordered | ||||
Sequence: HVEPASGFSGRHADGESGSPSSSSSGSLALGNSAIRGQAEVTRDPAPLLRGFRKPATGQMKRNRGEE | ||||||
Compositional bias | 196-213 | Polar residues | ||||
Sequence: GESGSPSSSSSGSLALGN | ||||||
Domain | 254-363 | DEUBAD | ||||
Sequence: PGSILVNTNLRALINSRTFHALPLHFQQQLLLLLPEVDRQVGTDGLLRLSGSALNNEFFTHAAQSWRERLADGEFTHEMQVRLRQEMEKEKKVEQWKEKFFEDYYGQKLG | ||||||
Region | 377-542 | Disordered | ||||
Sequence: EEAKVKSGLCVSGESVRPQRGPNTRQRDGHFKKRSRPDLRTRSRRNIYKKQEPEQAGVAKDASAAPDVSLSKDTKTDLAGVNSTPGPDVSSATSGQEGPKCPSEPVASQIQAERDNLACASASPDRIPTLPQDTVDQETKDQKRKSFEQEASASFPEKKPRLEDRQ | ||||||
Compositional bias | 397-432 | Basic and acidic residues | ||||
Sequence: GPNTRQRDGHFKKRSRPDLRTRSRRNIYKKQEPEQA | ||||||
Compositional bias | 451-474 | Polar residues | ||||
Sequence: KTDLAGVNSTPGPDVSSATSGQEG | ||||||
Compositional bias | 512-542 | Basic and acidic residues | ||||
Sequence: DQETKDQKRKSFEQEASASFPEKKPRLEDRQ | ||||||
Region | 634-822 | Disordered | ||||
Sequence: TTAIGGGGGPGGGGSGAIDEGGGRDSSSGDGSEACGHPEPRGAPSTSGESASDLQRTQLLPPCPLNGEHTPAEAAMPRARREDSASLRKEESCLLKRVPGVLTSGLEDASQPPIAPTGDQPCQALPPLSSQTPVAEMLTEQPKLLLDDRTECESSREDQGPTIPSESSSGRFPLGDLLGGGSDQAFDNM | ||||||
Compositional bias | 678-692 | Polar residues | ||||
Sequence: STSGESASDLQRTQL | ||||||
Compositional bias | 707-728 | Basic and acidic residues | ||||
Sequence: AAMPRARREDSASLRKEESCLL | ||||||
Compositional bias | 756-770 | Polar residues | ||||
Sequence: QALPPLSSQTPVAEM | ||||||
Compositional bias | 775-789 | Basic and acidic residues | ||||
Sequence: PKLLLDDRTECESSR | ||||||
Region | 894-913 | Disordered | ||||
Sequence: SDPESRENIPCPEPQDEKEW | ||||||
Region | 925-951 | Disordered | ||||
Sequence: SVPQPESCISHWTPPPAAVGSTGSDSE | ||||||
Region | 963-994 | Disordered | ||||
Sequence: ISEAPSPHSESTDTASDSEGHLSEDSSEVDAS | ||||||
Compositional bias | 976-990 | Basic and acidic residues | ||||
Sequence: TASDSEGHLSEDSSE | ||||||
Region | 1094-1130 | Disordered | ||||
Sequence: KVLPPGHRSSRLESSQLPLREQSQDRGTLQGTGENNR | ||||||
Compositional bias | 1102-1130 | Polar residues | ||||
Sequence: SSRLESSQLPLREQSQDRGTLQGTGENNR | ||||||
Compositional bias | 1178-1196 | Polar residues | ||||
Sequence: TSLDSQHPETELTPSSGNL | ||||||
Region | 1178-1198 | Disordered | ||||
Sequence: TSLDSQHPETELTPSSGNLEE | ||||||
Region | 1210-1233 | Disordered | ||||
Sequence: CEEQKEGHSLSQGSDPGAAPGQCL | ||||||
Region | 1255-1337 | Disordered | ||||
Sequence: SEQTDGTLSDQNNAGGHEKKLFGPGNTVTTLQCPRSEEQTPLPAEVPPVFPSRKIEPSKNSVSGGVQTTRENRMPKPPPVSAD | ||||||
Compositional bias | 1310-1324 | Polar residues | ||||
Sequence: EPSKNSVSGGVQTTR |
Sequence similarities
Belongs to the Asx family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,513
- Mass (Da)162,518
- Last updated2018-02-28 v1
- Checksum3A1EDE778B6430C3
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P59598 | ASXL1_MOUSE | Asxl1 | 1514 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 109-153 | Polar residues | ||||
Sequence: SCGSNEASTVSGENDVSLDETSSNASCSTESQSRPLSNPRDSHRA | ||||||
Compositional bias | 196-213 | Polar residues | ||||
Sequence: GESGSPSSSSSGSLALGN | ||||||
Compositional bias | 397-432 | Basic and acidic residues | ||||
Sequence: GPNTRQRDGHFKKRSRPDLRTRSRRNIYKKQEPEQA | ||||||
Compositional bias | 451-474 | Polar residues | ||||
Sequence: KTDLAGVNSTPGPDVSSATSGQEG | ||||||
Compositional bias | 512-542 | Basic and acidic residues | ||||
Sequence: DQETKDQKRKSFEQEASASFPEKKPRLEDRQ | ||||||
Compositional bias | 678-692 | Polar residues | ||||
Sequence: STSGESASDLQRTQL | ||||||
Compositional bias | 707-728 | Basic and acidic residues | ||||
Sequence: AAMPRARREDSASLRKEESCLL | ||||||
Compositional bias | 756-770 | Polar residues | ||||
Sequence: QALPPLSSQTPVAEM | ||||||
Compositional bias | 775-789 | Basic and acidic residues | ||||
Sequence: PKLLLDDRTECESSR | ||||||
Compositional bias | 976-990 | Basic and acidic residues | ||||
Sequence: TASDSEGHLSEDSSE | ||||||
Compositional bias | 1102-1130 | Polar residues | ||||
Sequence: SSRLESSQLPLREQSQDRGTLQGTGENNR | ||||||
Compositional bias | 1178-1196 | Polar residues | ||||
Sequence: TSLDSQHPETELTPSSGNL | ||||||
Compositional bias | 1310-1324 | Polar residues | ||||
Sequence: EPSKNSVSGGVQTTR |
Keywords
- Technical term