A0A2I2YHB9 · A0A2I2YHB9_GORGO
- ProteinTransient receptor potential cation channel subfamily M member 2
- GeneTRPM2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1553 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Gorilla
Accessions
- Primary accessionA0A2I2YHB9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 752-773 | Helical | ||||
Sequence: GLWRVTLCMLAFPLLLTGLISF | ||||||
Transmembrane | 794-818 | Helical | ||||
Sequence: APVVVFHLNILSYFAFLCLFAYVLM | ||||||
Transmembrane | 867-889 | Helical | ||||
Sequence: FWNKLDVGAILLFVAGLTCRLIP | ||||||
Transmembrane | 895-914 | Helical | ||||
Sequence: GRVILSLDFILFCLRLMHIF | ||||||
Transmembrane | 934-957 | Helical | ||||
Sequence: VFFFLFLLAVWVVSFGVAKQAILI | ||||||
Transmembrane | 1023-1045 | Helical | ||||
Sequence: WLTVLLLCLYLLFTNILLLNLLI |
Keywords
- Cellular component
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-20 | Disordered | ||||
Sequence: MEPSALRKAGSEQEEGFEGL | ||||||
Region | 1267-1286 | Disordered | ||||
Sequence: AAEELDAEPGGRKKTEEPGD | ||||||
Compositional bias | 1271-1286 | Basic and acidic residues | ||||
Sequence: LDAEPGGRKKTEEPGD | ||||||
Domain | 1404-1548 | Nudix hydrolase | ||||
Sequence: RWRRNEDGAICRKSIKKMLEVLVVKLPLSEHWALPGGSREPGETLPRKLKRILRQEHWPSFENLLKSGMEVYKGYMDDPRNTDNAWIETVAVSIHFQDQNDVELNRLNSNLHACDSGASIRWQVVDRRIPLYANHKTLLQKAAAE |
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,553
- Mass (Da)176,411
- Last updated2018-02-28 v1
- ChecksumA9005DA5AF1E92ED
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
G3QZC9 | G3QZC9_GORGO | TRPM2 | 1503 | ||
A0A2I2YI35 | A0A2I2YI35_GORGO | TRPM2 | 1503 | ||
A0A2I2ZIV0 | A0A2I2ZIV0_GORGO | TRPM2 | 215 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1271-1286 | Basic and acidic residues | ||||
Sequence: LDAEPGGRKKTEEPGD |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CABD030119543 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CABD030119544 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CABD030119545 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CABD030119546 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CABD030119547 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CABD030119548 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CABD030119549 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CABD030119550 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CABD030119551 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |