Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

A0A2I2YEE0 · A0A2I2YEE0_GORGO

Function

Catalytic activity

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentlysosomal membrane
Cellular Componentmethylosome
Cellular Componentnucleoplasm
Cellular Componentnucleus
Molecular FunctionGATOR1 complex binding
Molecular Functionhistone H4R3 methyltransferase activity
Molecular Functionhistone methyltransferase activity
Molecular Functionidentical protein binding
Molecular Functionmethyl-CpG binding
Molecular Functionmitogen-activated protein kinase p38 binding
Molecular Functionprotein-arginine omega-N asymmetric methyltransferase activity
Molecular Functionprotein-arginine omega-N monomethyltransferase activity
Molecular FunctionS-adenosyl-L-methionine binding
Biological Processcardiac muscle tissue development
Biological Processcellular response to methionine
Biological Processchromatin remodeling
Biological ProcessDNA damage response
Biological Processin utero embryonic development
Biological Processnegative regulation of JNK cascade
Biological Processnegative regulation of megakaryocyte differentiation
Biological Processneuron projection development
Biological Processpeptidyl-arginine methylation
Biological Processpositive regulation of cell population proliferation
Biological Processpositive regulation of double-strand break repair via homologous recombination
Biological Processpositive regulation of erythrocyte differentiation
Biological Processpositive regulation of TORC1 signaling
Biological Processpositive regulation of translation
Biological Processprotein homooligomerization
Biological Processregulation of BMP signaling pathway
Biological ProcessRNA splicing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    type I protein arginine methyltransferase
  • EC number

Gene names

    • Name
      PRMT1

Organism names

Accessions

  • Primary accession
    A0A2I2YEE0

Proteomes

Subcellular Location

Keywords

  • Cellular component

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain95-192Methyltransferase
Domain197-361Protein arginine N-methyltransferase

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    374
  • Mass (Da)
    43,078
  • Last updated
    2018-02-28 v1
  • MD5 Checksum
    54702B8CF846F02A8B42EBBA33EF7FBF
IKQDLLKNCILIRDRNFVATLANGMSLQPPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR

Computationally mapped potential isoform sequences

There are 7 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A2I2YQ01A0A2I2YQ01_GORGOPRMT1285
A0A2I2YXW8A0A2I2YXW8_GORGOPRMT1325
G3QE11G3QE11_GORGOPRMT1353
G3QE13G3QE13_GORGOPRMT1371
A0A2I2ZN45A0A2I2ZN45_GORGOPRMT1313
A0A2I2ZNT9A0A2I2ZNT9_GORGOPRMT1347
A0A2I2YLF8A0A2I2YLF8_GORGOPRMT1345

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CABD030114377
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CABD030114378
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CABD030114379
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CABD030114380
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CABD030114381
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help