A0A2I2Y902 · A0A2I2Y902_GORGO
- ProteinATP-binding cassette sub-family B member 6
- GeneABCB6
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids756 (go to sequence)
- Protein existencePredicted
- Annotation score5/5
Function
Catalytic activity
- heme b(in) + ATP + H2O = heme b(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.heme b (in)CHEBI:60344
+ CHEBI:30616 + CHEBI:15377 = heme b (out)CHEBI:60344+ CHEBI:456216 + CHEBI:43474 + CHEBI:15378 - pheophorbide a(in) + ATP + H2O = pheophorbide a(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
- protoporphyrin IX(in) + ATP + H2O = protoporphyrin IX(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
- uroporphyrin I(in) + ATP + H2O = uroporphyrin I(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
- uroporphyrin III(in) + ATP + H2O = uroporphyrin III(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
- coproporphyrin I(in) + ATP + H2O = coproporphyrin I(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
- coproporphyrin III(in) + ATP + H2O = coproporphyrin III(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
- coproporphyrinogen III(in) + ATP + H2O = coproporphyrinogen III(out) + ADP + phosphate + H+This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | endolysosome membrane | |
Cellular Component | endoplasmic reticulum membrane | |
Cellular Component | extracellular exosome | |
Cellular Component | Golgi apparatus | |
Cellular Component | melanosome membrane | |
Cellular Component | mitochondrial outer membrane | |
Cellular Component | multivesicular body membrane | |
Cellular Component | nucleoplasm | |
Cellular Component | plasma membrane | |
Cellular Component | vacuolar membrane | |
Molecular Function | ABC-type heme transporter activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | efflux transmembrane transporter activity | |
Molecular Function | heme binding | |
Biological Process | brain development | |
Biological Process | cellular detoxification of cadmium ion | |
Biological Process | heme metabolic process | |
Biological Process | heme transport | |
Biological Process | melanosome assembly | |
Biological Process | porphyrin-containing compound biosynthetic process | |
Biological Process | skin development | |
Biological Process | transmembrane transport |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-binding cassette sub-family B member 6
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Gorilla
Accessions
- Primary accessionA0A2I2Y902
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Endosome membrane ; Multi-pass membrane protein
Mitochondrion membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 27-49 | Helical | |||
Transmembrane | 70-93 | Helical | |||
Transmembrane | 105-127 | Helical | |||
Transmembrane | 148-168 | Helical | |||
Transmembrane | 188-207 | Helical | |||
Transmembrane | 383-405 | Helical | |||
Transmembrane | 411-432 | Helical | |||
Transmembrane | 503-521 | Helical | |||
Transmembrane | 533-551 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Expression
Gene expression databases
Interaction
Structure
Sequence
- Sequence statusComplete
- Length756
- Mass (Da)84,465
- Last updated2018-02-28 v1
- MD5 Checksum90CC22112B6382E446B2D621FBD77B7E
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A2I2YS67 | A0A2I2YS67_GORGO | ABCB6 | 742 | ||
A0A2I2YZH7 | A0A2I2YZH7_GORGO | ABCB6 | 745 | ||
A0A2I2YNA8 | A0A2I2YNA8_GORGO | ABCB6 | 730 |
Keywords
- Technical term