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A0A2I2Y902 · A0A2I2Y902_GORGO

Function

Catalytic activity

  • heme b(in) + ATP + H2O = heme b(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
    EC:7.6.2.5 (UniProtKB | ENZYME | Rhea)
  • pheophorbide a(in) + ATP + H2O = pheophorbide a(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • protoporphyrin IX(in) + ATP + H2O = protoporphyrin IX(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • uroporphyrin I(in) + ATP + H2O = uroporphyrin I(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • uroporphyrin III(in) + ATP + H2O = uroporphyrin III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrin I(in) + ATP + H2O = coproporphyrin I(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrin III(in) + ATP + H2O = coproporphyrin III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrinogen III(in) + ATP + H2O = coproporphyrinogen III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentendolysosome membrane
Cellular Componentendoplasmic reticulum membrane
Cellular Componentextracellular exosome
Cellular ComponentGolgi apparatus
Cellular Componentmelanosome membrane
Cellular Componentmitochondrial outer membrane
Cellular Componentmultivesicular body membrane
Cellular Componentnucleoplasm
Cellular Componentplasma membrane
Cellular Componentvacuolar membrane
Molecular FunctionABC-type heme transporter activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionefflux transmembrane transporter activity
Molecular Functionheme binding
Biological Processbrain development
Biological Processcellular detoxification of cadmium ion
Biological Processheme metabolic process
Biological Processheme transport
Biological Processmelanosome assembly
Biological Processporphyrin-containing compound biosynthetic process
Biological Processskin development
Biological Processtransmembrane transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-binding cassette sub-family B member 6
  • EC number
  • Alternative names
    • ABC-type heme transporter ABCB6

Gene names

    • Name
      ABCB6

Organism names

Accessions

  • Primary accession
    A0A2I2Y902

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Early endosome membrane
Endoplasmic reticulum membrane
; Multi-pass membrane protein
Endosome membrane
; Multi-pass membrane protein
Mitochondrion membrane
; Multi-pass membrane protein
Mitochondrion outer membrane

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane27-49Helical
Transmembrane70-93Helical
Transmembrane105-127Helical
Transmembrane148-168Helical
Transmembrane188-207Helical
Transmembrane383-405Helical
Transmembrane411-432Helical
Transmembrane503-521Helical
Transmembrane533-551Helical

Keywords

PTM/Processing

Keywords

Expression

Gene expression databases

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain266-556ABC transmembrane type-1

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    756
  • Mass (Da)
    84,465
  • Last updated
    2018-02-28 v1
  • MD5 Checksum
    90CC22112B6382E446B2D621FBD77B7E
MVTVGNYCEAEGPVGPAWMQDGLSPCFFFTLVPSTRMALGTLALVLALPCRRRERPAGADSLSWGAGPRISPYVLQLLLATLQAALPLAGLAGRVGTARGAPLPSYLLLASVLESLAGACGLWLLVVERSQARQRLAMGIWIKFRHSPGLLLLWTVAFAAENLALVSWNSPQWWWARADLGQQVQFSLWVLRYVVSGGLFVLGLWAPGLRPQSYTLRVHEEDQDVERSQVRSAAQQSTWRDFGRKLRLLSGYLWPRGSPALQLVVLICLGLMGLERALNVLVPIFYRNIVNLLTEKAPWNSLAWTVTSYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQFTSRRVELLIFSHLHELSLRWHLGRRTGEVLRIADRGTSSVTGLLSYLVFNVIPTLADIIIGIIYFSMFFNAWFGLIVFLCMSLYLTLTIVVTEWRTKFRRAMNTQENATRARAVDSLLNFETVKYYNAESYEVERYREAIIKYQGLEWKSSASLVLLNQTQNLVIGLGLLAGSLLCAYFVSEQKLQVGDYVLFGTYIIQLYMPLNWFGTYYRMIQTNFIDMENMFDLLKEETEVKDLPGAGPLRFQKGRIEFENVHFSYADGGGAGPTSSSGDGRCLLSNPTFPCRRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQDISQVGLLWRRLYSPVKDLYGAIKATKGRAQWLMPIIPALWEAEAGGSLEPSSSRPAWATWQNTLSTKNTKIAGRGGSRL

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A2I2YS67A0A2I2YS67_GORGOABCB6742
A0A2I2YZH7A0A2I2YZH7_GORGOABCB6745
A0A2I2YNA8A0A2I2YNA8_GORGOABCB6730

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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