A0A2I0UKQ1 · A0A2I0UKQ1_LIMLA
- ProteinPeroxisomal trans-2-enoyl-CoA reductase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids278 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Participates in chain elongation of fatty acids. Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA. Has no 2,4-dienoyl-CoA reductase activity.
Catalytic activity
- (2E)-decenoyl-CoA + NADPH + H+ = decanoyl-CoA + NADP+This reaction proceeds in the forward direction.
- (2E)-dodecenoyl-CoA + NADPH + H+ = dodecanoyl-CoA + NADP+This reaction proceeds in the forward direction.
- (2E)-hexenoyl-CoA + NADPH + H+ = hexanoyl-CoA + NADP+This reaction proceeds in the forward direction.
- (2E)-octenoyl-CoA + NADPH + H+ = octanoyl-CoA + NADP+This reaction proceeds in the forward direction.
- (2E)-tetradecenoyl-CoA + NADPH + H+ = tetradecanoyl-CoA + NADP+This reaction proceeds in the forward direction.
Pathway
Lipid metabolism.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | peroxisome | |
Molecular Function | trans-2-enoyl-CoA reductase (NADPH) activity | |
Biological Process | phytol metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePeroxisomal trans-2-enoyl-CoA reductase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Charadriiformes > Scolopacidae > Limosa
Accessions
- Primary accessionA0A2I0UKQ1
Proteomes
Subcellular Location
PTM/Processing
Keywords
- PTM
Interaction
Subunit
Interacts with PEX5, probably required to target it into peroxisomes.
Structure
Sequence
- Sequence statusComplete
- Length278
- Mass (Da)29,878
- Last updated2018-02-28 v1
- Checksum213067F3C2AAAF61
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KZ505705 EMBL· GenBank· DDBJ | PKU46588.1 EMBL· GenBank· DDBJ | Genomic DNA |