A0A2I0UKQ1 · A0A2I0UKQ1_LIMLA

Function

function

Participates in chain elongation of fatty acids. Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA. Has no 2,4-dienoyl-CoA reductase activity.

Catalytic activity

  • (2E)-decenoyl-CoA + NADPH + H+ = decanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-dodecenoyl-CoA + NADPH + H+ = dodecanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-hexenoyl-CoA + NADPH + H+ = hexanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-octenoyl-CoA + NADPH + H+ = octanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-tetradecenoyl-CoA + NADPH + H+ = tetradecanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • a (2E)-enoyl-CoA + NADPH + H+ = a 2,3-saturated acyl-CoA + NADP+
    This reaction proceeds in the forward direction.
    EC:1.3.1.38 (UniProtKB | ENZYME | Rhea)

Pathway

Lipid metabolism.

GO annotations

AspectTerm
Cellular Componentperoxisome
Molecular Functiontrans-2-enoyl-CoA reductase (NADPH) activity
Biological Processphytol metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Peroxisomal trans-2-enoyl-CoA reductase
  • EC number

Gene names

    • ORF names
      llap_3145

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Charadriiformes > Scolopacidae > Limosa

Accessions

  • Primary accession
    A0A2I0UKQ1

Proteomes

Subcellular Location

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Interacts with PEX5, probably required to target it into peroxisomes.

Family & Domains

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    278
  • Mass (Da)
    29,878
  • Last updated
    2018-02-28 v1
  • Checksum
    213067F3C2AAAF61
MMKGKTATEENAQTGGCSVVIASRKFDRLKAAAEELNNSFSSMSPAKVTPIQCNIRNEDEVEALMKSTLSLHGKIDFLVNNGGGQFTSPSEAIRAKGWNAVIDTNLTGTFYCCKAVYNAWMQEHGGVIVNITAAVRNGFPGMSHTAAARAAVNNLTKTLALEWAHSGVRINSVAPGLVFSETAVANYGEQGIMLWLKTIPKIPAKRSAVPEEISPAVCFLLSPAASFITGITMVVDGGQSLYSHALEIPDHDRWPSPPEGKNSEMLQRLLSGKFKPKL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KZ505705
EMBL· GenBank· DDBJ
PKU46588.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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