A0A2I0TT16 · A0A2I0TT16_LIMLA

  • Protein
    receptor protein-tyrosine kinase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for binding site, active site.

113851002003004005006007008009001,0001,1001,2001,300
Type
IDPosition(s)Description
Binding site1098-1106ATP (UniProtKB | ChEBI)
Binding site1124ATP (UniProtKB | ChEBI)
Active site1188Proton acceptor
Binding site1192ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentbasal plasma membrane
Cellular Componentreceptor complex
Molecular FunctionATP binding
Molecular Functionhepatocyte growth factor receptor activity
Biological Processcell migration
Biological Processliver development
Biological Processneuron differentiation
Biological Processpancreas development
Biological Processpositive regulation of kinase activity
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    receptor protein-tyrosine kinase
  • EC number

Gene names

    • ORF names
      llap_12743

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Charadriiformes > Scolopacidae > Limosa

Accessions

  • Primary accession
    A0A2I0TT16

Proteomes

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane964-987Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond, modified residue.

Type
IDPosition(s)Description
Signal1-21
ChainPRO_501419601722-1385receptor protein-tyrosine kinase
Disulfide bond100↔103
Disulfide bond130↔138
Disulfide bond169↔172
Disulfide bond293↔363
Disulfide bond381↔402
Disulfide bond382↔417
Disulfide bond521↔539
Disulfide bond527↔561
Disulfide bond530↔546
Disulfide bond542↔552
Modified residue1218Phosphotyrosine; by autocatalysis
Modified residue1219Phosphotyrosine; by autocatalysis
Modified residue1333Phosphotyrosine; by autocatalysis
Modified residue1340Phosphotyrosine; by autocatalysis

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain27-516Sema
Domain1092-1325Protein kinase
Region1345-1385Disordered
Compositional bias1358-1385Acidic residues

Sequence similarities

Belongs to the plexin family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,385
  • Mass (Da)
    151,847
  • Last updated
    2018-02-28 v1
  • Checksum
    032224F8E9232481
MGPSCCVCLSLMLALAPLGAGAWQCPRIPYSSTRNFSVPYVLPSLNAGSPVQNVAVFTDSSGPAAIFVAVRNRILLASPELRILSVLVTGPVGSAECEICRLCPATTEGPEDTDNVLLLLDPLEPWLYSCGTAQHGLCYQHQLEVQDGKVAITTTRCLYSARGNNATFCPDCVASPLGTTATVVATSYASSFYLGSTVNSSVAARYSPQSVSVRRLKGTLDGFSDDFQWLTVLPQYQDNYTIHYVHSFADGDHVYLLTVQPERPGSATYHTRLARLSTQERDLRRYRELVLDCRFESKRRRRSVEGDTERDVTYNVLQAAHAARPGARLARELGINDTDTVLFGAFAESRPESRVPREDSAVCAFPLHLLNQAMEEGMEKCCSTGHQPLLRGLSFFQPVEYCPHNVNLSAPVVNTRCWDKPTLVPATSYKVDLFNGHLAGVLLTSIFVTALGDVTVAHLGTAEGRIFQMVLQRSSSYLLTLANFSLGEPGPVRGAMGLQSDSLFFTAGTKVWRLNVTGPGCRHFSTCQRCLRAERFMGCGWCGDGCTRRHECPGLWVQDSCPPVLTDFHPRSAPLQGRTRVTLCGMTFHSHLDLDPRRSPPRDYRVMVGQRGCAVLPEESRSLRPLPTSRRKDFVDVLVCELEPGGPMVVGGPADVVLTVKEPAGPSGFRIHGSATLGGFIFVEPSISTLHPTFGPQGGGTHLSLHGTNLSAGSSWRVLVNGSECPLAGQPRQGDGVIRCTAPAAGGLGNAWVSLWIDGEEFLAPVPFRYRPNPVVSAINPNCSYEGSMLTIIGTHLDSVYRAKIRFESSAVRTEATECESPQAPERLLCRSPAFPFESKVETAPGNLSVLLDGTAGRWLFRLRYYSRPKVFPLEKEGGRLRLKPGEDEIEVHQLGLDAVAACMNITMTVGSRDCHPNVLKNEVTCRLPRELRLPPDGAPVEICVNGACNALGWVLPAATSLDLAASLALGTSITFLVCCILAAVLFRWRWRKRRGTETLELLVQPGRNDTTTTTQRPGVDYREVLVLPPGGSPSPVGPRARFAGVSAGAGMAGGGSPVPLLRSTSCCLEDLRPELLEEVKDILIPEERLITHRHQVIGKGHFGSVYHGTYMDPLLGELHCAVKSLHRITDVEEVEEFLREGILMKSFHHPQVLSLLGSPTVKDLIGFGLQVALGMEYLAQKKFVHRDLAARNCMLDETLTVKVADFGLARDVFGKEYYSIQQHRHAKLPVKWMALESLQTQKFTTKSDVWSFGVLMWELLTRGASPYPGVDPYDMARYLLRGRRLPQPRHCPDTLYGVMLSCWAPAPEERPSFTGLVGELKRVLATLEGEHYVNLAVTYINLERGPPFPPAPPGQLPDGEDEDEENTEYEEEEEEEEEEDTAVC

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1358-1385Acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KZ507378
EMBL· GenBank· DDBJ
PKU36954.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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