A0A2I0TII8 · A0A2I0TII8_LIMLA

Function

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionamino acid binding
Molecular Functionaspartate carbamoyltransferase activity
Molecular FunctionATP binding
Molecular Functioncarbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Molecular Functiondihydroorotase activity
Molecular Functionmetal ion binding
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological Process'de novo' UMP biosynthetic process
Biological Processcitrulline biosynthetic process
Biological Processglutamine metabolic process
Biological ProcessUTP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • Cad protein

Gene names

    • ORF names
      llap_16111

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Charadriiformes > Scolopacidae > Limosa

Accessions

  • Primary accession
    A0A2I0TII8

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain309-501ATP-grasp
Domain845-1036ATP-grasp
Domain1101-1259MGS-like
Region1641-1677Disordered
Compositional bias1660-1677Basic and acidic residues

Sequence similarities

In the 2nd section; belongs to the CarB family.
In the 3rd section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.
In the C-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
In the N-terminal section; belongs to the CarA family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,006
  • Mass (Da)
    220,608
  • Last updated
    2018-02-28 v1
  • Checksum
    362FC0336D0CC09E
MWFESSKIHVAALVVGECSETPSHWSASRSLDQWLKEQNIPGLEGVDTRALTKKIREKGTLLGKLVPDGTPENSLTFEDPNKRHLVQEVSLKTPCVFNPSGSLRIMAVDCGLKYNQHKPFFSVQFHPEHRAGPTDLEGLFDIFVGAARDLRSGDGSAQTVRERLRDWLTYEEAPARGQDAARPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTVLINPNIATVQTSKGLADKVYFLPITPEYVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLERYRVRVLGTPVASIEMTEDRKVFVEKMEEIGEHVAPSEAAASLEQALAAAERLGYPVLVRSAYALGGLGSGFANNREELVALVSQAFTHTSQVLVDKSLKGWKEIEYEVVRDAYNNCITVCNMENLDPLGIHTGESIVVAPSQTLNDTEYFLLRRTAVKVVRHLGIVGECNIQFALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPLLRNSVTNSTTANFEPSLDYCVVKIPRWDLSKFLRVSTKIGSSMKSVGEVMAIGRNFEEAFQKALRMVDENCVGFDHTVKLASDVELETPTDKRIFVLAAALRAGYSIERLYELTKIDRWFLHKMKNITDHAVLLESYREEQSTMPPAVLQRAKQLGFSDKQVALAVLSTELAVRKMRRDLKILPVVKQIDTVAAEWPAQTNYLYLTYNGTEHDLAFREPHVMVIGSGVYRIGSSVEFDWCAVGCIQELRKMGFKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNIAMALHRQQCRILGTSPEAIDSAENRFKFSRLLDSIGISQPLWKELSDMESAKHFCCKVGYPCVVRPSYVLSGAAMNVAYSDSDLEKFLSNAVAVSKEQPVVISKFIQEAKEIDVDAVACDGVVVAIAISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALASQVIMGEDVEPVGLMTGTGIVGVKVPQFSFSRLAGADVVLGVEMTSTGEVACFGENRCEAYLKAMLSTGFKIPKKNILLTIGSYKNKSELLPTVRTLESLGYKLYASLGTADFYTEHGIKVMAVDWHFEEAEGSEAGARETQQRSILDYLAENHFEMVINLSMRNSGGRRLSSFVTKGYRTRRLAVDYSVPLIIDIKCTKLFVEALGQIGAAPPLKIHVDCMTSQKLIRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVCAMPNTSPAITDATSFALAQKLAEAGARCDFALFLGASSENAGALGPLAGAAAGLKMYLNDTFSSLRMDDVSLWMEHFEQWPQHLPVVAHAERQTVAAVLMVAQLYQRPVHICHVARREEILLIKAAKQKGVPVTCEVAPHHLFLSQDDLGRLGEGRAAVRPVLGTRQDVEALWDNMDTIDCFATDHAPHTLEEKQGPEPPPGYPGLETMLPLLLTAVSEGRLTVEDIIQRLYENPRKIFGLPAQEDTYVEVDLEHEWIIPSHMAFSKAHWTPFEGMKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVKKWSSGAVLPPHAAPAKESVKTPERPRHVAAGEMLRGRASSPRRAGPMGEGRFHLPPRIHRASDPGLPAEDARDKAGRKAVEADPTAIQDSYFYPLGPFPRQASPQGTPHFQTSPLLHPLVGQHVLSVQHFSKEQLSHLFNVAHTLRMLVQKERSLDILKGKVMASMFYEASTRTSSSFAAAMSRLGGSVLSFSEATSSVQKGESLADSVQTMCCYADVLVLRHPQPGAVELAAKHCRKPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLARLLTQYRVNLRYVTPPGLRMPPDITSFVASKGIKQEEFGSIEEALPDTDVLYMTRIQKERFRLPEEYEAVSAGGDTSVEVDSDPRAAYFRQAENGMYMRMALLATVLGRF

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1660-1677Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KZ509943
EMBL· GenBank· DDBJ
PKU33585.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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