A0A2I0TA71 · A0A2I0TA71_LIMLA
- ProteinMetal cation symporter ZIP14
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids132 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- 2 hydrogencarbonate(out) + Mn2+(out) = 2 hydrogencarbonate(in) + Mn2+(in)This reaction proceeds in the forward direction.
2 hydrogencarbonate (out)CHEBI:17544+ Mn2+ (out)CHEBI:29035= 2 hydrogencarbonate (in)CHEBI:17544+ Mn2+ (in)CHEBI:29035 - 2 hydrogencarbonate(out) + Zn2+(out) = 2 hydrogencarbonate(in) + Zn2+(in)This reaction proceeds in the forward direction.
- Cd2+(out) + 2 hydrogencarbonate(out) = Cd2+(in) + 2 hydrogencarbonate(in)This reaction proceeds in the forward direction.
- Fe2+(out) + 2 hydrogencarbonate(out) = Fe2+(in) + 2 hydrogencarbonate(in)This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | apical plasma membrane | |
Cellular Component | basolateral plasma membrane | |
Cellular Component | early endosome membrane | |
Cellular Component | late endosome membrane | |
Cellular Component | lateral plasma membrane | |
Cellular Component | lysosomal membrane | |
Molecular Function | monoatomic cation:bicarbonate symporter activity | |
Molecular Function | zinc ion transmembrane transporter activity | |
Biological Process | zinc ion import across plasma membrane |
Names & Taxonomy
Protein names
- Recommended nameMetal cation symporter ZIP14
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Charadriiformes > Scolopacidae > Limosa
Accessions
- Primary accessionA0A2I0TA71
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Apical cell membrane ; Multi-pass membrane protein
Basolateral cell membrane ; Multi-pass membrane protein
Early endosome membrane ; Multi-pass membrane protein
Endosome membrane ; Multi-pass membrane protein
Late endosome membrane ; Multi-pass membrane protein
Lateral cell membrane ; Multi-pass membrane protein
Lysosome membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 6-25 | Helical | ||||
Sequence: YGFLCVTVISLCSLVGASVV | ||||||
Transmembrane | 37-58 | Helical | ||||
Sequence: LLYFIALAIGTLYSNALFQLIP | ||||||
Transmembrane | 70-87 | Helical | ||||
Sequence: YISKSAVVFGGFYLFFFT |
Keywords
- Cellular component
Interaction
Subunit
Homotrimer.
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 101-132 | Disordered | ||||
Sequence: HHHGHSHYGPEALPSKKDQEDGRAGVQDPFWG | ||||||
Compositional bias | 104-124 | Basic and acidic residues | ||||
Sequence: GHSHYGPEALPSKKDQEDGRA |
Sequence similarities
Belongs to the ZIP transporter (TC 2.A.5) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length132
- Mass (Da)14,960
- Last updated2018-02-28 v1
- Checksum17D8C641D4A8BDDE
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 104-124 | Basic and acidic residues | ||||
Sequence: GHSHYGPEALPSKKDQEDGRA |
Keywords
- Technical term