A0A2I0JBN5 · A0A2I0JBN5_PUNGR
- ProteinDNA polymerase epsilon catalytic subunit
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1122 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
DNA polymerase II participates in chromosomal DNA replication.
Catalytic activity
- a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)
Cofactor
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | epsilon DNA polymerase complex | |
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | DNA binding | |
Molecular Function | DNA-directed DNA polymerase activity | |
Molecular Function | single-stranded DNA 3'-5' DNA exonuclease activity | |
Molecular Function | zinc ion binding | |
Biological Process | base-excision repair, gap-filling | |
Biological Process | DNA replication proofreading | |
Biological Process | leading strand elongation | |
Biological Process | mitotic cell cycle | |
Biological Process | nucleotide-excision repair, DNA gap filling |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA polymerase epsilon catalytic subunit
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Myrtales > Lythraceae > Punica
Accessions
- Primary accessionA0A2I0JBN5
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 149-172 | Disordered | ||||
Sequence: QKEISKESEHQDPSSMQQQAMPVQ | ||||||
Region | 198-223 | Disordered | ||||
Sequence: KKRQRLGNSKNSHLTNGPFKLVDDGM | ||||||
Domain | 431-816 | DNA polymerase epsilon catalytic subunit A C-terminal | ||||
Sequence: FLDKQFRDACQALDIESPLLQNGATFKVDYVGHVKDAEKILLRSINEHRHDDHGPTIAVTESPEMHLLRSSIQALDDFPCVSIPSNARDSQYPAVGWQQVAARIGMQRCAASSRWLNERISLARYAHVPVGNFELDWLMFTADIFFSRALRDQQQVLWISENGVPDLGGTNDEDTCFADEVHQPVLIYPGAYRKVSVELKIHHLAVNALLKSNQVNEIEGGALLSFDEDAGSGLNASDKKYAYDDTTSCASAFRVLKQLIQRCLADAVTSGNIYADALLQHLYRWLCSPKSKLHDPALHRMLHKVMQKVFALLLAELRKLGASIIFANFSKVIIDTGKYDISAARAYSDSLVKTLQNRDLFEWIELEPVQFWHSLLYMDQYNYGGI |
Sequence similarities
Belongs to the DNA polymerase type-B family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,122
- Mass (Da)128,192
- Last updated2018-02-28 v1
- Checksum4CE47868F40576CD
Keywords
- Technical term