A0A2I0FSG1 · A0A2I0FSG1_9GAMM
- ProteinRibonuclease H
- GenernhA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids192 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Catalytic activity
Cofactor
Note: Binds 1 Mg2+ ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | membrane | |
Molecular Function | magnesium ion binding | |
Molecular Function | nucleic acid binding | |
Molecular Function | RNA-DNA hybrid ribonuclease activity | |
Biological Process | DNA replication, removal of RNA primer |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibonuclease H
- EC number
- Short namesRNase H
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales
Accessions
- Primary accessionA0A2I0FSG1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 12-30 | Helical | ||||
Sequence: IWRVIAVLIALVYVRLGVF |
Keywords
- Cellular component
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 38-179 | RNase H type-1 | ||||
Sequence: MMKQVEIFTDGSCLGNPGPGGYGAILRYRQHEKTFSAGFTLTTNNRMEMMAAIVALEALSEPCSVVLSTDSQYVRQGITSWIHNWKKRGWKTADKKPVKNVDLWKRLDSALSHHEIKWEWVKGHAGHPENERCDELAREAAN |
Sequence similarities
Belongs to the RNase H family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length192
- Mass (Da)21,538
- Last updated2018-02-28 v1
- ChecksumC23F72871C848273
Keywords
- Technical term