A0A2I0BYK4 · A0A2I0BYK4_PLAFO

Function

function

Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (archaeal/eukaryal route): step 2/2.

Features

Showing features for site, binding site.

TypeIDPosition(s)Description
Site79May act as a substrate filter by repelling compounds with a negatively charged alpha-carboxylate
Binding site80pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site102substrate
Binding site103substrate
Binding site110substrate
Binding site318substrate
Binding site407tRNA (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionO-phosphoseryl-tRNA(Sec) selenium transferase activity
Molecular FunctiontRNA binding
Biological Processconversion of seryl-tRNAsec to selenocys-tRNAsec
Biological Processselenocysteine incorporation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    O-phosphoseryl-tRNA(Sec) selenium transferase
  • EC number
  • Alternative names
    • Selenocysteine synthase
    • Selenocysteinyl-tRNA(Sec) synthase
    • Sep-tRNA:Sec-tRNA synthase

Gene names

    • ORF names
      CK202_1807
      , CYL21_4782

Organism names

  • Taxonomic identifier
  • Strain
    • NF54
  • Taxonomic lineage
    Eukaryota > Sar > Alveolata > Apicomplexa > Aconoidasida > Haemosporida > Plasmodiidae > Plasmodium > Plasmodium (Laverania)

Accessions

  • Primary accession
    A0A2I0BYK4

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue289N6-(pyridoxal phosphate)lysine

Family & Domains

Sequence similarities

Belongs to the SepSecS family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    578
  • Mass (Da)
    66,815
  • Last updated
    2018-02-28 v1
  • Checksum
    D83089B47FE5B413
MNETLCDNNKAPKGGMKTSKKYSLISNQTLNQKENTIWNIVNNGRLPNYGLNEISVMNILYQISSQNLCNSEKNVKIGERENRIYSSIVRSKYIGFGHGIGRSGNLDDVQPKSAGNSILAKLTSSFVKDLIRNFGIKSCEDVYILPYATGMCLSTCLLYLKQIREDSQYVIISRIDHKTCYKCISFCNLKYFVVDMIYKNEELYTDLEGIEKLLEEYKEKICCVMSATSVYAPRNSDDIIKIAHICKKYNTPHIINNAFGLQCTYICKEIQKCFESQGRVDFVVQSCDKNFLVPVNGGIIFSSNREQMKLLKKSYPGRTPVNAYLDLFITLLEMGKDKIMNLRKERVDNFNWLKEKIQLLCLKYNLELIKTSKNFISMAINLNHMYTHCNTDNPKVINMLGSMLFYRNVTGHRVICSPLLNRNYLLKKAREKYMNMLENKKGNDAMMITSNESNEENVKRDLSKKEADIYDNMYSNGFDEIKSVENDMLQNKSNIIKAYEKQIEEEFDKLNEPNTIVIGNHKFKNFGSSYNSYPISYIAFSCVVGIERPELENFVSKLDNAIDYFIKFFKKKKEEELK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QFXU01000022
EMBL· GenBank· DDBJ
KAF4327291.1
EMBL· GenBank· DDBJ
Genomic DNA
NYMT01000004
EMBL· GenBank· DDBJ
PKC48386.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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