A0A2I0BYK4 · A0A2I0BYK4_PLAFO
- ProteinO-phosphoseryl-tRNA(Sec) selenium transferase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids578 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
Catalytic activity
- O-phospho-L-seryl-tRNA(Sec) + selenophosphate + H2O = L-selenocysteinyl-tRNA(Sec) + 2 phosphate
Cofactor
Pathway
Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (archaeal/eukaryal route): step 2/2.
Features
Showing features for site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 79 | May act as a substrate filter by repelling compounds with a negatively charged alpha-carboxylate | ||||
Sequence: E | ||||||
Binding site | 80 | pyridoxal 5'-phosphate (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 102 | substrate | ||||
Sequence: R | ||||||
Binding site | 103 | substrate | ||||
Sequence: S | ||||||
Binding site | 110 | substrate | ||||
Sequence: Q | ||||||
Binding site | 318 | substrate | ||||
Sequence: R | ||||||
Binding site | 407 | tRNA (UniProtKB | ChEBI) | ||||
Sequence: R |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | O-phosphoseryl-tRNA(Sec) selenium transferase activity | |
Molecular Function | tRNA binding | |
Biological Process | conversion of seryl-tRNAsec to selenocys-tRNAsec | |
Biological Process | selenocysteine incorporation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameO-phosphoseryl-tRNA(Sec) selenium transferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Sar > Alveolata > Apicomplexa > Aconoidasida > Haemosporida > Plasmodiidae > Plasmodium > Plasmodium (Laverania)
Accessions
- Primary accessionA0A2I0BYK4
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Modified residue | 289 | N6-(pyridoxal phosphate)lysine | ||||
Sequence: K |
Structure
Sequence
- Sequence statusComplete
- Length578
- Mass (Da)66,815
- Last updated2018-02-28 v1
- ChecksumD83089B47FE5B413