A0A2I0BQQ8 · A0A2I0BQQ8_PLAFO
- ProteinMitochondrial coenzyme A transporter SLC25A42
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids340 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate.
Catalytic activity
- 3'-dephospho-CoA(in) + ADP(out) = 3'-dephospho-CoA(out) + ADP(in)3'-dephospho-CoA (in)CHEBI:57328
+ ADP (out)CHEBI:456216= 3'-dephospho-CoA (out)CHEBI:57328+ ADP (in)CHEBI:456216 - ADP(in) + ATP(out) = ADP(out) + ATP(in)
- AMP(in) + ADP(out) = AMP(out) + ADP(in)
- ADP(out) + CoA(in) = ADP(in) + CoA(out)
- dADP(in) + ADP(out) = dADP(out) + ADP(in)
- adenosine 3',5'-bisphosphate(in) + ADP(out) = adenosine 3',5'-bisphosphate(out) + ADP(in)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Biological Process | transmembrane transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameMitochondrial coenzyme A transporter SLC25A42
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Sar > Alveolata > Apicomplexa > Aconoidasida > Haemosporida > Plasmodiidae > Plasmodium > Plasmodium (Laverania)
Accessions
- Primary accessionA0A2I0BQQ8
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 81-101 | Helical | ||||
Sequence: WWGYNASICNFLSFSFLRLLF | ||||||
Transmembrane | 122-139 | Helical | ||||
Sequence: FSLLYFSSCLAASIAYPF | ||||||
Transmembrane | 243-264 | Helical | ||||
Sequence: FFSYIALGVITGYVAQMVTYPL |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Repeat | 16-108 | Solcar | ||||
Sequence: ELFITTFLTHGGSNIISKLIISPLERIVLIKQIQPILFKNVLIEPSYTYRNIINSIRTNQGYTSFWWGYNASICNFLSFSFLRLLFHDQIKYN |
Sequence similarities
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length340
- Mass (Da)41,010
- Last updated2018-02-28 v1
- Checksum98E0C681AEB375E4