A0A2I0APY7 · A0A2I0APY7_9ASPA

  • Protein
    Phosphatidyl-N-methylethanolamine N-methyltransferase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Lipid metabolism.
Phospholipid metabolism; phosphatidylcholine biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site371-373S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site451-452S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionphosphatidyl-N-dimethylethanolamine N-methyltransferase activity
Molecular Functionphosphatidyl-N-methylethanolamine N-methyltransferase activity
Molecular Functionphosphatidylethanolamine N-methyltransferase activity
Biological Processmethylation
Biological Processphosphatidylcholine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphatidyl-N-methylethanolamine N-methyltransferase
  • EC number
  • Alternative names
    • Phospholipid methyltransferase
      (PLMT
      )

Gene names

    • ORF names
      AXF42_Ash018596

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • cv. Shenzhen
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Asparagales > Orchidaceae > Apostasioideae > Apostasia

Accessions

  • Primary accession
    A0A2I0APY7

Proteomes

Subcellular Location

Endoplasmic reticulum membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, transmembrane, intramembrane.

TypeIDPosition(s)Description
Topological domain1-298Lumenal
Transmembrane295-318Helical
Intramembrane299-319Helical
Transmembrane415-440Helical
Topological domain450-461Cytoplasmic

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region144-210Disordered
Compositional bias186-203Basic and acidic residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    461
  • Mass (Da)
    52,555
  • Last updated
    2018-02-28 v1
  • Checksum
    5E871EA7038C702D
MPSFLTATSTPQSARRSPFLERESFGRTEKVYAIERTEREREEREGGERRVRKWVRRAHSIFKVGWVRTAPHHGKRRQEFSLRSSLLCAQILFLRIKKRPTRSTGLQRTNPTGGTAMEQMRSAYAPISPEAKRKNLLIDGREKADTPESLQSTQHRNEAVTVRNRGSGPLLFEQVRAAKSANGNSGKHKINREIEEDGRRPPTSSEHSNNIISLGGETIKELERSRRIAACGRERQKPAKQGEQEQRQRAFVAFAGQRKELIDKFWGDGWDRTEPATESAPRLGNHRLFGQGSMAAAAATAAVVLGTMAPFPFYYFLWSYPQAWVNLCGKGVDPCHRMAQISHALKLVQFASILLVARFSWPPWYYIVLLSLGQYLNFKVYQLLGEAGTYYGVRFGKNIPWVMEFPFGYIKDPQYVGSILSLVACSCWVPLKYLLLWILGYMFMMRVESMEDPATRAKPFS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias186-203Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KZ451963
EMBL· GenBank· DDBJ
PKA57621.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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