A0A2H9T8M7 · A0A2H9T8M7_9ZZZZ

  • Protein
    glycerol-3-phosphate dehydrogenase
  • Gene
    glpA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Protein has several cofactor binding sites:
FAD (UniProtKB | Rhea| CHEBI:57692 )

FMN (UniProtKB | Rhea| CHEBI:58210 )

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentglycerol-3-phosphate dehydrogenase (FAD) complex
Cellular Componentplasma membrane
Molecular Functionflavin adenine dinucleotide binding
Molecular FunctionFMN binding
Molecular Functionglycerol-3-phosphate dehydrogenase (quinone) activity
Biological Processglycerol catabolic process
Biological Processglycerol-3-phosphate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    glycerol-3-phosphate dehydrogenase
  • EC number

Gene names

    • Name
      glpA
    • ORF names
      CI610_01480

Organism names

Accessions

  • Primary accession
    A0A2H9T8M7

Subcellular Location

Membrane
; Peripheral membrane protein

Keywords

Interaction

Subunit

Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain7-355FAD dependent oxidoreductase
Compositional bias377-400Polar residues
Region377-402Disordered
Domain424-476BFD-like [2Fe-2S]-binding

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    539
  • Mass (Da)
    59,132
  • Last updated
    2018-02-28 v1
  • Checksum
    ED466047196F70AC
MKNIERDVVIIGGGATGAGILRDCALRGIHAILLEKGDIAWGTTGRNHGLLHSGARYAVTDAPSAKECIKENRILKNIARHCVEDTGGLFLTLPDDSLEYQEKFIKSCHQANIDAKRLTPEQALQLEPSANPAMIGAVKVPDGSIDPFRLTASNILDAEEHGSEIMTYTEVTGLLKHQGRVTGVECINTKTGEKLAIHGQQVVNACGIWGQKIAEYADLSIKMMPSKGTLLIIDYRLNRMVLNRCRKPADADILVPGDTVSVIGTTSIKIPYDQIDNPPIDPEEVDLLIREGEKLAPALGRSRIVRAYAGVRPLVASDGESGRNVSRGIVLLDHQSLDNLPGFITIAGGKLMTYRLMAEETTNLIAKHLGNTAPCTTATEKLPGAEETTKPSSSLSRPLSGSAVYRHGQRANKFLSDTPEEKTIVCECEMVSRGEIDYAIKELNAISLEDLRRRTRLGMGPCQGEVCTCRAANILNRSKTIKEYDPINDIHDFLEERWKGNRPVLWGDTLRESEFSHWIYQSLLGYDTLKNTSETTAEQ

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias377-400Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NSIT01000062
EMBL· GenBank· DDBJ
PJE79539.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp