A0A2H5VE29 · A0A2H5VE29_UNCAD

  • Protein
    Anthranilate phosphoribosyltransferase
  • Gene
    trpD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per monomer.

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site805-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site80anthranilate 1 (UniProtKB | ChEBI)
Binding site83-845-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site885-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site90-935-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site92Mg2+ 1 (UniProtKB | ChEBI)
Binding site108-1165-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site111anthranilate 1 (UniProtKB | ChEBI)
Binding site1205-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site166anthranilate 2 (UniProtKB | ChEBI)
Binding site223Mg2+ 2 (UniProtKB | ChEBI)
Binding site224Mg2+ 2 (UniProtKB | ChEBI)
Binding site224Mg2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionanthranilate phosphoribosyltransferase activity
Molecular Functionmagnesium ion binding
Biological Processtryptophan biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Anthranilate phosphoribosyltransferase
  • EC number

Gene names

    • Name
      trpD
    • ORF names
      HRbin06_00261

Organism names

Accessions

  • Primary accession
    A0A2H5VE29

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-65Glycosyl transferase family 3 N-terminal
Domain75-322Glycosyl transferase family 3

Sequence similarities

Belongs to the anthranilate phosphoribosyltransferase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    347
  • Mass (Da)
    38,198
  • Last updated
    2018-02-28 v1
  • MD5 Checksum
    40E645F476C92408EC3F2E6640FF1D09
MIREALSKLVEFKDLSSEEAYLSLKEIMDKKTNEIQISAFLTALRMKGEKVEEIVGLAKAMLDSCIKIKPEVKLLVDTCGTGGDKFKTVNVSTIASFIIAGLGISVAKHGNRAFTSKCGSADVLEALGYNLDLEAEKVKDMIEKIGFGFLFAPKFHIAMKEVAKVRRDLGFRTIFNILGPLTNPSNPNFQLIGVFEPTLVKKMAESLRSLGKEGIVVYGDGMDEINLASENLVAFVKEDVKILKLKSKDFGLEKVKEEDLMVRDFQDNVDSMFKILYGLDKSPKLNICLANAAALIYGCSRAENLIDAFSFAEESVKSGKAYKVLKESVKFSGGNIALLESLEKKYG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BEHI01000026
EMBL· GenBank· DDBJ
GBC74953.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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