A0A2H5VDE2 · A0A2H5VDE2_UNCAD

  • Protein
    NAD kinase
  • Gene
    ppnK_1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site50Proton acceptor
Binding site121-122NAD+ (UniProtKB | ChEBI)
Binding site151NAD+ (UniProtKB | ChEBI)
Binding site162-167NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular FunctionNAD+ kinase activity
Biological ProcessNAD metabolic process
Biological ProcessNADP biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD kinase
  • EC number
  • Alternative names
    • ATP-dependent NAD kinase

Gene names

    • Name
      ppnK_1
    • Synonyms
      nadK
    • ORF names
      HRbin06_00020

Organism names

Accessions

  • Primary accession
    A0A2H5VDE2

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the NAD kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    330
  • Mass (Da)
    37,496
  • Last updated
    2018-02-28 v1
  • MD5 Checksum
    16F7C8C143872BD9BBD239283EBDA50A
MRVGLILSKLASKRKEEISKRLEASGLKYKILDKIEFLQEFDILMVIGSDKNVLEVFQQMKEETIPLLGVSETDELGFLVEKSINQLEDILKSLANKDYKIEEASRLYVKVDDKEEAYALNEIALFPKKSATLMEYRLVVDDEFIWRDYSDGVIISTPTGSTAYAMSAGGPTLLPTSRAFVIVPVNSMDITRKPLVINEESKIYINEIASRVDCQVIVDGVKRIKIDKFLKATKAKTQAKLIRITKSSPAIDRITKKVKLAEELIKMPPSAKLVLKTLQYEGPLSRKELIEKTMLPERTARMALSLLTQKGLVKRKSTLRDARRKFYYVL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BEHI01000002
EMBL· GenBank· DDBJ
GBC74713.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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