A0A2H4VK16 · A0A2H4VK16_9EURY
- ProteinDNA polymerase beta
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids566 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- 2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H+
- ATP + O-(5'-adenylyl)-L-tyrosyl-[protein] = diphosphate + O-[5'-(adenylyl-(5'->3')-adenylyl)]-L-tyrosyl-[protein]
- a 5'-end 2'-deoxyribose-2'-deoxyribonucleotide-DNA = (2E,4S)-4-hydroxypenten-2-al-5-phosphate + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H+
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | DNA binding | |
Molecular Function | DNA-directed DNA polymerase activity | |
Molecular Function | phosphoric ester hydrolase activity | |
Molecular Function | zinc ion binding | |
Biological Process | DNA repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA polymerase beta
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Methanomada group > Methanobacteria > Methanobacteriales > Methanobacteriaceae > Methanobacterium
Accessions
- Primary accessionA0A2H4VK16
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-312 | DNA-directed DNA polymerase X | ||||
Sequence: MQNQKVASILNRVADYLEMDGPDFRTKAYRRAAHTIETLSVDIADIKKQGKLEELPGIGKHIHAKIEEILDTGSLEYLENLKKEFPLDLDALMSVEGLGPKKIKLLYQELGIKNLDDLEKEAKRHHIRRLKGMGAKTEAKILQNLEFARKSTGRQLLGEVLPLSSLIKQRISALDLVEQVEIAGSIRRRKETVGDIDVLTVTQHPDEVMDFFNRMDLVEEVIVKGHSKSTVRLFNGMDADIRVFKEDDFGSAMVYFTGSRELNISLRKIAISQGMKLNEYGVFHDEKRLAGKTEVDVFQALGMDYIPPELRE | ||||||
Domain | 50-69 | Helix-hairpin-helix DNA-binding motif class 1 | ||||
Sequence: GKLEELPGIGKHIHAKIEEI | ||||||
Domain | 90-109 | Helix-hairpin-helix DNA-binding motif class 1 | ||||
Sequence: DALMSVEGLGPKKIKLLYQE | ||||||
Domain | 125-144 | Helix-hairpin-helix DNA-binding motif class 1 | ||||
Sequence: HHIRRLKGMGAKTEAKILQN | ||||||
Domain | 336-414 | Polymerase/histidinol phosphatase N-terminal | ||||
Sequence: GDLHIHTNWSDGKSSIMEMALEASQRDYEYLAITDHTRIPVARGMDENRLIKQMGEIDRVNHELEDITLLKGAEVNLDS |
Family and domain databases
Sequence
- Sequence statusComplete
- Length566
- Mass (Da)64,400
- Last updated2018-02-28 v1
- Checksum4577847A116A3E31
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP017767 EMBL· GenBank· DDBJ | AUB58424.1 EMBL· GenBank· DDBJ | Genomic DNA |