A0A2H1KVC1 · A0A2H1KVC1_9MICO

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

TypeIDPosition(s)Description
Site104Transition state stabilizer
Active site108Proton acceptor
Binding site272Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      BAURA86_03384

Organism names

  • Taxonomic identifier
  • Strain
    • 8(6)
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Brevibacteriaceae > Brevibacterium

Accessions

  • Primary accession
    A0A2H1KVC1

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link231↔257Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-107)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-37Disordered
Domain141-430Plant heme peroxidase family profile
Domain513-724Plant heme peroxidase family profile

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    734
  • Mass (Da)
    80,687
  • Last updated
    2018-01-31 v1
  • Checksum
    93B897B67C2AA117
MTESSTGGCPVAHTTSATPAPETESLAAPSQGDANSHWWPNRLNLKILAKNQPARDPMDEGFDYDAEFASLDYFALKADIEELQKTNADWWSADFGHYGPFMIRMAWHSAGTYRVQDGRGGGGEGQQRFAPLNSWPDNVGLDKARRLLWPVKKKYGKKISWADLFILAGNVGLESMGFKTFGYAGGRKDVWEPDNDVYWGSETEWLGTDKRYVGNRELQKPLAATTMGLIYVNPEGPEGKPDPLAAALDIRETFARMAMDDEETVALIAGGHTFGKTHGAAPESHKGGDPEAAPIEEQGLGWKSDFGTGQGNDTVGSGIEVTWTYHPTRWDNEFFHILFAYEWEVFENEGGHLQWRPVDGGGDDMVPMAQGDGRREPRMLTTDLSLRFDPIYEKISRRFKDDQKAFEDVFARAWFKLTHRDMGPATRYLGPEVPEEELIWQDPVPEGTPLDEAGLEAVKAAIRNSGLTVSQLVSTTWAAASTHRRSDFRGGVNGGRLRLEPQKSWDVNEPAKLDQVVSVLEGIAADNGASFADVLAIAGAVGVETAAKAAGHDVSVPVTTGRGDATQEQTDVNSFSFLEPTHDGFRNYLTEGLPLSAEHLLLDRASLLGLTPSELTVLIGGLRVLGANYEDSELGVFTDRPGELTNDFFVNLLELGNVWKPVGPSESANVYECFSPAGEKLWTGSRIDLLFGANSELRAIAEVYASDDAKDKFVNDFVKAWSKLVEADRFDLHR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FXZI01000015
EMBL· GenBank· DDBJ
SMY03514.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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