A0A2G9EFE2 · A0A2G9EFE2_9FUSO

Function

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Probably binds two magnesium or manganese ions per subunit.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site, active site, site.

125320406080100120140160180200220240
TypeIDPosition(s)Description
Binding site7Mg2+ 1 (UniProtKB | ChEBI)
Binding site35Mg2+ 1 (UniProtKB | ChEBI)
Active site105
Active site144Proton donor/acceptor
Binding site144Mg2+ 1 (UniProtKB | ChEBI)
Binding site146Mg2+ 1 (UniProtKB | ChEBI)
Site146Transition state stabilizer
Site216Important for catalytic activity
Binding site241Mg2+ 1 (UniProtKB | ChEBI)
Active site242Proton acceptor
Binding site242Mg2+ 1 (UniProtKB | ChEBI)
Site242Interaction with DNA substrate

GO annotations

AspectTerm
Molecular FunctionDNA binding
Molecular Functiondouble-stranded DNA 3'-5' DNA exonuclease activity
Molecular Functionendonuclease activity
Molecular Functionmetal ion binding
Biological ProcessDNA repair

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Exodeoxyribonuclease III

Gene names

    • Name
      xth
    • ORF names
      CTM71_04235
      , CTM72_06545
      , CTM86_10070

Organism names

  • Taxonomic identifier
  • Strains
    • KCOM 1259
    • KCOM 1261
    • KCOM 1282
  • Taxonomic lineage
    Bacteria > Fusobacteriota > Fusobacteriia > Fusobacteriales > Fusobacteriaceae > Fusobacterium

Accessions

  • Primary accession
    A0A2G9EFE2

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-242Endonuclease/exonuclease/phosphatase

Sequence similarities

Belongs to the DNA repair enzymes AP/ExoA family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    253
  • Mass (Da)
    29,803
  • Last updated
    2018-01-31 v1
  • Checksum
    8A42196A8307BF53
MKLISWNVNGIRAAIKKGFLDYFNEQNADIFCLQETKLSAGQLDLELKGYHQYWNYAEKKGYSGTAIFTKEEPLSVSYGLGIEEHDKEGRVITLEFEKFYMITVYTPNSKDELLRLDYRMVWEDEFRKYLKNLEKKKPVVVCGDLNVAHKEIDLKNPKTNRRNAGFTDEERGKFTELLESGFIDTFRYFYPDLEHAYSWWSYRANARKNNTGWRIDYFVVSKALEKYLVDAEIHAQTEGSDHCPVVLFLDFKK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP024699
EMBL· GenBank· DDBJ
ATV59423.1
EMBL· GenBank· DDBJ
Genomic DNA
CP024702
EMBL· GenBank· DDBJ
ATV66885.1
EMBL· GenBank· DDBJ
Genomic DNA
PEQY01000001
EMBL· GenBank· DDBJ
PIM79657.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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