A0A2G8Y760 · A0A2G8Y760_TOXGO
- ProteinMitogen-activated protein kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids685 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Cofactor
Activity regulation
Activated by threonine and tyrosine phosphorylation.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | ATP binding | |
Molecular Function | MAP kinase activity | |
Molecular Function | protein serine kinase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMitogen-activated protein kinase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Sar > Alveolata > Apicomplexa > Conoidasida > Coccidia > Eucoccidiorida > Eimeriorina > Sarcocystidae > Toxoplasma
Accessions
- Primary accessionA0A2G8Y760
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 13-306 | Protein kinase | ||||
Sequence: YDILQKLGKGAYGIVWKSTDRRTNETVALKKIFDAFQNATDAQRTFREIMFLQELAGHENIVRLKNVLKADNDKDIYLVFDYMETDLHAVIRADILEEIHKQYIVYQLLRAIKYMHSGELLHRDMKPSNVLLNSECQVKVADFGLARSVAHSESNNSEAGGNPVLTDYVATRWYRAPEILLGSTSYTKGVDMWSLGCILGELLSGRPIFPGTSTMNQLERIMTLTGRPSPEDVDAVKSPFAATMMESLPLGKVKNFKDAFPNASPEALDLLKQLLQFNPNKRISAEKGLEHPYV | ||||||
Region | 345-590 | Disordered | ||||
Sequence: VIKKKHDQRRHRTAGSSGRHHSSHHSSGTRSSSSSSSSSANPRTSSSAQHRNSQSRPAGSSQTSASPQASHNPRSGSSSSSYTGSSSASHPTGASAQAPSHFGSSHYASSHQMHRSGSFVRDRPPAYASSTSGVSHYPHYPASSSSVSSSHHGVSSSHHGVSSSPQGVSSSHHGVSSSHHGVSSSHHGVSSSHHGVSSSHHGVSSSHHGVSSSHHGVSPQMSPGMSTATSGGSVHARDRPAASGSS | ||||||
Compositional bias | 349-370 | Basic residues | ||||
Sequence: KHDQRRHRTAGSSGRHHSSHHS | ||||||
Compositional bias | 371-459 | Polar residues | ||||
Sequence: SGTRSSSSSSSSSANPRTSSSAQHRNSQSRPAGSSQTSASPQASHNPRSGSSSSSYTGSSSASHPTGASAQAPSHFGSSHYASSHQMHR | ||||||
Compositional bias | 472-577 | Polar residues | ||||
Sequence: ASSTSGVSHYPHYPASSSSVSSSHHGVSSSHHGVSSSPQGVSSSHHGVSSSHHGVSSSHHGVSSSHHGVSSSHHGVSSSHHGVSSSHHGVSPQMSPGMSTATSGGS | ||||||
Compositional bias | 607-622 | Polar residues | ||||
Sequence: SATHSPQLSGSSRLAG | ||||||
Region | 607-685 | Disordered | ||||
Sequence: SATHSPQLSGSSRLAGQSAEGVAAHAVSRGESFHGPVRAKTDTHTHVGVSRAVSGTPQWTDIERHHSHAVKSASKTYNS |
Sequence similarities
Family and domain databases
Sequence
- Sequence statusComplete
- Length685
- Mass (Da)73,772
- Last updated2018-01-31 v1
- ChecksumA058E2F8A6DDD12F
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 349-370 | Basic residues | ||||
Sequence: KHDQRRHRTAGSSGRHHSSHHS | ||||||
Compositional bias | 371-459 | Polar residues | ||||
Sequence: SGTRSSSSSSSSSANPRTSSSAQHRNSQSRPAGSSQTSASPQASHNPRSGSSSSSYTGSSSASHPTGASAQAPSHFGSSHYASSHQMHR | ||||||
Compositional bias | 472-577 | Polar residues | ||||
Sequence: ASSTSGVSHYPHYPASSSSVSSSHHGVSSSHHGVSSSPQGVSSSHHGVSSSHHGVSSSHHGVSSSHHGVSSSHHGVSSSHHGVSSSHHGVSPQMSPGMSTATSGGS | ||||||
Compositional bias | 607-622 | Polar residues | ||||
Sequence: SATHSPQLSGSSRLAG |