A0A2G6P4M5 · A0A2G6P4M5_UNCDL

Function

function

Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.
Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site289-294ATP (UniProtKB | ChEBI)
Binding site293Mg2+ (UniProtKB | ChEBI)
Binding site311substrate
Binding site335substrate
Binding site357substrate
Binding site394ATP (UniProtKB | ChEBI)
Binding site408substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionmagnesium ion binding
Molecular FunctionNADP binding
Molecular Functionshikimate 3-dehydrogenase (NADP+) activity
Molecular Functionshikimate kinase activity
Biological Processamino acid biosynthetic process
Biological Processaromatic amino acid family biosynthetic process
Biological Processchorismate biosynthetic process
Biological Processphosphorylation
Biological Processshikimate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Shikimate kinase
  • EC number
  • Short names
    SK

Gene names

    • Name
      aroK
    • ORF names
      CSA15_02995

Organism names

Accessions

  • Primary accession
    A0A2G6P4M5

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain33-113Shikimate dehydrogenase substrate binding N-terminal
Domain138-220Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase

Sequence similarities

Belongs to the shikimate kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    443
  • Mass (Da)
    50,538
  • Last updated
    2018-01-31 v1
  • Checksum
    D88CCD60A283511A
MIFTNLLKTLIEKILFLRSFMNISDKEFNLYGVVGSPIGHSKSPDIFNSIISKYNKKGRYIRLAVSDSSRIIPLCKELNIRGINITSPYKEVLFNELDSYDKISESLEAVNTISFENGSSIGFNSDSYGVYSSINRYDLKSRSILVIGGGGAAKSVLYALKKFNITITNRTESKGLKLATAFGVKFIQFSDIEKGVKKADIVISTLPDPEIVLKPQWFRKGSIFFDANYKSKFILPQTVNYISGKDWLINQAIPNLKRFFLLDVDYKEVLSNLEKVESKKNITLIGFMGCGKTTYGRKLAKKIGRSWIDLDSEIEKENGASICEIFEKYGEERFREIETKILERYSNIDNCLISCGGGIVESERNREILRSTYNIWIYLSFENCYNRIKNSKKRPLVGKDLRLIYERRIDLYSMVTDLLFDSFGDIEKGVDYLSKEIKVSGVI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PDTR01000055
EMBL· GenBank· DDBJ
PIE79482.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp