A0A2G6P0A6 · A0A2G6P0A6_UNCDL
- ProteinMultifunctional fusion protein
- Genepgk
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids658 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
Catalytic activity
- (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.
Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 21-23 | substrate | ||||
Sequence: DFN | ||||||
Binding site | 37 | substrate | ||||
Sequence: R | ||||||
Binding site | 60-63 | substrate | ||||
Sequence: HFGR | ||||||
Binding site | 119 | substrate | ||||
Sequence: R | ||||||
Binding site | 152 | substrate | ||||
Sequence: R | ||||||
Binding site | 203 | ATP (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 325 | ATP (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 355-358 | ATP (UniProtKB | ChEBI) | ||||
Sequence: GGDT | ||||||
Binding site | 412-414 | substrate | ||||
Sequence: NWK | ||||||
Active site | 498 | Electrophile | ||||
Sequence: H | ||||||
Active site | 570 | Proton acceptor | ||||
Sequence: E | ||||||
Binding site | 576 | substrate | ||||
Sequence: G | ||||||
Binding site | 616 | substrate | ||||
Sequence: S | ||||||
Binding site | 637-638 | substrate | ||||
Sequence: GG |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ADP binding | |
Molecular Function | ATP binding | |
Molecular Function | phosphoglycerate kinase activity | |
Molecular Function | triose-phosphate isomerase activity | |
Biological Process | gluconeogenesis | |
Biological Process | glycolytic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMultifunctional fusion protein
Including 2 domains:
- Recommended nameTriosephosphate isomerase
- EC number
- Short namesTIM ; TPI
- Alternative names
- Recommended namePhosphoglycerate kinase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Candidatus Delongiibacteriota
Accessions
- Primary accessionA0A2G6P0A6
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Monomer.
Structure
Sequence
- Sequence statusComplete
- Length658
- Mass (Da)72,674
- Last updated2018-01-31 v1
- ChecksumEBE62BB650A7AC08