A0A2G6H343 · A0A2G6H343_UNCBA
- ProteinPhosphoheptose isomerase
- GenegmhA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids192 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
Miscellaneous
The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.
Catalytic activity
- 2 D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 51-53 | substrate | |||
Binding site | 60 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 64 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 64 | substrate | |||
Binding site | 92-93 | substrate | |||
Binding site | 118-120 | substrate | |||
Binding site | 123 | substrate | |||
Binding site | 171 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 171 | substrate | |||
Binding site | 179 | Zn2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | carbohydrate derivative binding | |
Molecular Function | D-sedoheptulose 7-phosphate isomerase activity | |
Molecular Function | zinc ion binding | |
Biological Process | carbohydrate metabolic process | |
Biological Process | D-glycero-D-manno-heptose 7-phosphate biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoheptose isomerase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota
Accessions
- Primary accessionA0A2G6H343
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length192
- Mass (Da)20,455
- Last updated2018-01-31 v1
- MD5 ChecksumB36456975DDBFE7044A058D604C71E04
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
PDRI01000028 EMBL· GenBank· DDBJ | PID92661.1 EMBL· GenBank· DDBJ | Genomic DNA |