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A0A2G6H343 · A0A2G6H343_UNCBA

  • Protein
    Phosphoheptose isomerase
  • Gene
    gmhA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.

Miscellaneous

The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site51-53substrate
Binding site60Zn2+ (UniProtKB | ChEBI)
Binding site64Zn2+ (UniProtKB | ChEBI)
Binding site64substrate
Binding site92-93substrate
Binding site118-120substrate
Binding site123substrate
Binding site171Zn2+ (UniProtKB | ChEBI)
Binding site171substrate
Binding site179Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncarbohydrate derivative binding
Molecular FunctionD-sedoheptulose 7-phosphate isomerase activity
Molecular Functionzinc ion binding
Biological Processcarbohydrate metabolic process
Biological ProcessD-glycero-D-manno-heptose 7-phosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoheptose isomerase
  • EC number
  • Alternative names
    • Sedoheptulose 7-phosphate isomerase

Gene names

    • Name
      gmhA
    • ORF names
      CSA96_02185

Organism names

Accessions

  • Primary accession
    A0A2G6H343

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain36-192SIS

Sequence similarities

Belongs to the SIS family. GmhA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    192
  • Mass (Da)
    20,455
  • Last updated
    2018-01-31 v1
  • MD5 Checksum
    B36456975DDBFE7044A058D604C71E04
MKTSINASLEEARRVLDDFMSDAAKIEAIEGAAQLMLASIRKGGKIISCGNGGSMTDAMHFAEELSGVFRHKRPALPALSISDPSHLSCVANDCGFETVFSRYVEGLGMSGDLLLAISTSGNSPNILNAATAAREKGMKVVALTGKDGGKLASMSDVEIRVSGGRYSDRIQELHIKVLHILVQLIEEQLHLS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PDRI01000028
EMBL· GenBank· DDBJ
PID92661.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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