A0A2G6FGD6 · A0A2G6FGD6_UNCDU

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

TypeIDPosition(s)Description
Site93Transition state stabilizer
Active site97Proton acceptor
Binding site260Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processhydrogen peroxide catabolic process
Biological Processresponse to oxidative stress

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      CSB33_03825

Organism names

  • Taxonomic identifier
  • Strain
    • DOLZORAL124_58_51
  • Taxonomic lineage
    Bacteria > Thermodesulfobacteriota > Desulfobacteria > Desulfobacterales

Accessions

  • Primary accession
    A0A2G6FGD6

Proteomes

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link219↔245Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-96)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-20Polar residues
Region1-25Disordered
Domain130-422Plant heme peroxidase family profile
Region269-307Disordered
Compositional bias289-307Polar residues

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    731
  • Mass (Da)
    80,359
  • Last updated
    2018-01-31 v1
  • Checksum
    FB3655AC5FBA9E2D
MNDKSRCPVTGKSGSQAAGGGASNRDWWPDQINLEILHQHSAKSSPMGEDFNYAEEFNKLDLEALKKDIFEVMTNSQDWWPADYGHYGPLFIRMAWHSAGTYRMGDGRGGGGTGNQRLAPVNSWPDNVNLDKARRLLWPVKQKYGRKISWADLIIFAGNCAIESMGLKPFGFGGGREDVWEPERDIYWGAEDTWLGDDRYKGDRELDNPLAAVQMGLIYVNPEGPSGNPDVLASGRDVRETFARMAMNDEETVALVAGGHTFGKCHGAGDAARVGPEPEGAGLSEQGLGWKSSHGSGSGDDTISSGIEGAWTPNPIKWDNAYFDMLFGYDWNLEKSPAGAWQWVPVNPEEKDFAPAAHDAARKVKTIMTTADLSLRMDPIYKPIAKRFQENPEEFADAFVRAWFKLTHRDMGPRSRYLGGMVPDEELIWQDPVPAVDHELIDDQDAAALKEAVLAAGPSISRLVYTAWSSASTFRGSDMRGGANGARIRLAPQKDWDVNEPEELEKVLKALSSVRDAFNKAQSGGKRVSLADLIVLAGCAAVEKAAAAAGVSITVPFTPGRTDATDEQTDAESFDVLEPVADGFRNYLKGRYSVTAEELLIDRAQLLTLTAPEMTVLIGGLRVLNANFGRSPLGVFTDRPGVLSNDFFVNLLNMDTAWKPVSEAEDMFEGRDRATGELRWTGSRIDLLFGSNSQLRSIAEVYACEDSEKKFVEDFVAAWVKVMNLDRFDVS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-20Polar residues
Compositional bias289-307Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
PDQM01000021
EMBL· GenBank· DDBJ
PID73375.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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