A0A2G6BPZ9 · A0A2G6BPZ9_UNCCC
- ProteinPhosphopantetheine adenylyltransferase
- GenecoaD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids161 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
Catalytic activity
- (R)-4'-phosphopantetheine + ATP + H+ = 3'-dephospho-CoA + diphosphate
Cofactor
Pathway
Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.
Features
Showing features for binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 9 | substrate | |||
Binding site | 9-10 | ATP (UniProtKB | ChEBI) | |||
Binding site | 17 | ATP (UniProtKB | ChEBI) | |||
Site | 17 | Transition state stabilizer | |||
Binding site | 41 | substrate | |||
Binding site | 73 | substrate | |||
Binding site | 87 | substrate | |||
Binding site | 88-90 | ATP (UniProtKB | ChEBI) | |||
Binding site | 98 | ATP (UniProtKB | ChEBI) | |||
Binding site | 123-129 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | pantetheine-phosphate adenylyltransferase activity | |
Biological Process | coenzyme A biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphopantetheine adenylyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Candidatus Cloacimonadota
Accessions
- Primary accessionA0A2G6BPZ9
Proteomes
Subcellular Location
Interaction
Subunit
Homohexamer.
Structure
Sequence
- Sequence statusComplete
- Length161
- Mass (Da)18,059
- Last updated2018-01-31 v1
- Checksum96231176D1288CA4
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
PDON01000060 EMBL· GenBank· DDBJ | PID27381.1 EMBL· GenBank· DDBJ | Genomic DNA |