A0A2G5ID46 · CTB4_CERBT

Function

function

MFS transporter; part of the gene cluster that mediates the biosynthesis of cercosporin, a light-activated, non-host-selective toxin (By similarity).
The perylenequinone chromophore of cercosporin absorbs light energy to attain an electronically-activated triplet state and produces active oxygen species such as the hydroxyl radical, superoxide, hydrogen peroxide or singlet oxygen upon reaction with oxygen molecules (PubMed:11701851).
These reactive oxygen species cause damage to various cellular components including lipids, proteins and nucleic acids (PubMed:11701851).
Responsible for secretion and accumulation of cercosporin, but does not play any roles in self-protection against the toxicity of cercosporin (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular Functiontransmembrane transporter activity

Names & Taxonomy

Protein names

  • Recommended name
    Cercosporin MFS transporter CTB4
  • Alternative names
    • Cercosporin toxin biosynthesis cluster protein 4

Gene names

    • Name
      CTB4
    • ORF names
      CB0940_00831

Organism names

Accessions

  • Primary accession
    A0A2G5ID46

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane72-92Helical
Transmembrane110-130Helical
Transmembrane142-162Helical
Transmembrane170-190Helical
Transmembrane202-222Helical
Transmembrane230-250Helical
Transmembrane306-326Helical
Transmembrane343-363Helical
Transmembrane383-403Helical
Transmembrane407-427Helical
Transmembrane456-476Helical
Transmembrane480-500Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004498671-512Cercosporin MFS transporter CTB4

Family & Domains

Sequence similarities

Belongs to the major facilitator superfamily. CAR1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    512
  • Mass (Da)
    56,047
  • Last updated
    2018-01-31 v1
  • Checksum
    BD321384E9191C90
MALPITDDDLDGLKQPYVTFSSGSASPPQSTTDAMDLEEQVLDAIKSDAFLVDWVGEDDKGNPQNLPYWRKWVITMSLALYALSTTFSSSVFGAATHVLAEEFALPAETVVLGCTSLFMVGFATGPIFWGPFSEAFGRTRPLLAGYLAFAVLQLPIADARSLTSICILRFLGGFFGAAPSSILSGILADIWSPRERGFAMPTVGAFLTIGPILGPLIGSVLVQSVLGWRWIANVVAIASFFIAVFTFPFLPETYTPLLLARRAERMRHMTRNWAYRSKSEEAQSSIGDFAERYLLRPARMLALEPILLMMTLYVSVSFGLLYNFFLAYPTSFIQERGWDQTTASLPLISILVGVIIAGALLSFTTNSRWAPNAKEGRPQETRLLLMMVGAVSLPAGMFLFAWTSSATMNPWPQILSGIPTGFGIHLINMQGMNYIIDSYKIYANSAIAANTFLRSLFAAGFPILATSMYAAIGVKWGTTILALLAVAMIPIPILFYYFGAKIRAKSKWQPPL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LKMD01000100
EMBL· GenBank· DDBJ
PIB02403.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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