A0A2G5G2I7 · A0A2G5G2I7_9PSED
- ProteintRNA pseudouridine synthase A
- GenetruA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids287 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
Catalytic activity
- uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA
RHEA-COMP:10085 = RHEA-COMP:10087
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 70 | Nucleophile | ||||
Sequence: D | ||||||
Binding site | 128 | substrate | ||||
Sequence: Y |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | RNA binding | |
Molecular Function | tRNA pseudouridine(38-40) synthase activity | |
Biological Process | tRNA pseudouridine synthesis |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA pseudouridine synthase A
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionA0A2G5G2I7
Proteomes
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 25-121 | Pseudouridine synthase I TruA alpha/beta | ||||
Sequence: EYKGARYRGFQRQGANVPSIQGHLENALSKVAGGAPVSILCAGRTDASVHSSGQVVHFDTTVERSLHAWIMGANMNLPGDISVTWAKVMPAHFHARF | ||||||
Domain | 161-263 | Pseudouridine synthase I TruA alpha/beta | ||||
Sequence: AAQALVGTHDFSAFRATRCQAKSPIKTVHHLQLIEHGRFIVLDIRANAFLHHMVRNIAGVLMTIGAGERPPEWAREVLERGDRHSGGVTAHPYGLYLIQVDYP |
Sequence similarities
Belongs to the tRNA pseudouridine synthase TruA family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length287
- Mass (Da)31,852
- Last updated2018-01-31 v1
- Checksum6D393062A5850839