A0A2G5CGI5 · A0A2G5CGI5_AQUCA
- ProteinEndonuclease/exonuclease/phosphatase domain-containing protein
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids307 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Cofactor
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Note: Probably binds two magnesium or manganese ions per subunit.
Features
Showing features for active site, binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 131 | ||||
Active site | 171 | ||||
Binding site | 171 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 173 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Site | 173 | Transition state stabilizer | |||
Site | 260 | Important for catalytic activity | |||
Binding site | 291 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Active site | 292 | Proton acceptor | |||
Binding site | 292 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Site | 292 | Interaction with DNA substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA-(apurinic or apyrimidinic site) endonuclease activity | |
Molecular Function | double-stranded DNA 3'-5' DNA exonuclease activity | |
Molecular Function | metal ion binding | |
Molecular Function | phosphoric diester hydrolase activity | |
Biological Process | base-excision repair |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameEndonuclease/exonuclease/phosphatase domain-containing protein
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Ranunculales > Ranunculaceae > Thalictroideae > Aquilegia
Accessions
- Primary accessionA0A2G5CGI5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-16 | ||||
Chain | PRO_5013875462 | 17-307 | Endonuclease/exonuclease/phosphatase domain-containing protein | ||
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 35-59 | Disordered | |||
Compositional bias | 43-57 | Basic and acidic residues | |||
Domain | 72-292 | Endonuclease/exonuclease/phosphatase | |||
Sequence similarities
Belongs to the DNA repair enzymes AP/ExoA family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length307
- Mass (Da)34,920
- Last updated2018-01-31 v1
- MD5 ChecksumAB859ADE8C47B7A261143E2AFFBA86A5
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A2G5CGH1 | A0A2G5CGH1_AQUCA | AQUCO_05600082v1 | 362 | ||
A0A2G5CGH9 | A0A2G5CGH9_AQUCA | AQUCO_05600082v1 | 361 | ||
A0A2G5CGN6 | A0A2G5CGN6_AQUCA | AQUCO_05600082v1 | 277 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 43-57 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KZ305073 EMBL· GenBank· DDBJ | PIA30395.1 EMBL· GenBank· DDBJ | Genomic DNA |