A0A2G5CGI5 · A0A2G5CGI5_AQUCA

Function

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Probably binds two magnesium or manganese ions per subunit.

Features

Showing features for active site, binding site, site.

130720406080100120140160180200220240260280300
Type
IDPosition(s)Description
Active site131
Active site171
Binding site171Mg2+ 1 (UniProtKB | ChEBI)
Binding site173Mg2+ 1 (UniProtKB | ChEBI)
Site173Transition state stabilizer
Site260Important for catalytic activity
Binding site291Mg2+ 1 (UniProtKB | ChEBI)
Active site292Proton acceptor
Binding site292Mg2+ 1 (UniProtKB | ChEBI)
Site292Interaction with DNA substrate

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA-(apurinic or apyrimidinic site) endonuclease activity
Molecular Functiondouble-stranded DNA 3'-5' DNA exonuclease activity
Molecular Functionmetal ion binding
Molecular Functionphosphoric diester hydrolase activity
Biological Processbase-excision repair

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Endonuclease/exonuclease/phosphatase domain-containing protein

Gene names

    • ORF names
      AQUCO_05600082v1

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Goldsmith
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Ranunculales > Ranunculaceae > Thalictroideae > Aquilegia

Accessions

  • Primary accession
    A0A2G5CGI5

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-16
ChainPRO_501387546217-307Endonuclease/exonuclease/phosphatase domain-containing protein

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region35-59Disordered
Compositional bias43-57Basic and acidic residues
Domain72-292Endonuclease/exonuclease/phosphatase

Sequence similarities

Belongs to the DNA repair enzymes AP/ExoA family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    307
  • Mass (Da)
    34,920
  • Last updated
    2018-01-31 v1
  • MD5 Checksum
    AB859ADE8C47B7A261143E2AFFBA86A5
MLIVFFFVLKTTGLSSLSFLKNLILMSLPYRMPAAGSKGSPKNPGELKDDTSSSREEKQTLMRAISSPPLQNYHVWWSLSDSKYAGTALFVKKCIQPKKVSFSLDGKASKHEPDGRVILAEFESFRLLNTYAPNNGWKEEENSFPRRRKWDKRILEFVAQSTDKPLIWCGDLNVSHQEIDVSHPDFFSSAKVNNYIPPNKEDCGQPGFTLNERKRFSTILSEGKLVDAYRFLHKEKDIEHGFSWSGNPVGKYRGKRMRIDYFIVSEKLKDKIVSCEMHGQGIELEGFYGSDHCPVSLELSSVDSSES

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A2G5CGH1A0A2G5CGH1_AQUCAAQUCO_05600082v1362
A0A2G5CGH9A0A2G5CGH9_AQUCAAQUCO_05600082v1361
A0A2G5CGN6A0A2G5CGN6_AQUCAAQUCO_05600082v1277

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias43-57Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KZ305073
EMBL· GenBank· DDBJ
PIA30395.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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