A0A2E4DCD5 · A0A2E4DCD5_9BACT
- ProteinRibonuclease H
- GenernhA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids192 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Catalytic activity
Cofactor
Note: Binds 1 Mg2+ ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | magnesium ion binding | |
Molecular Function | nucleic acid binding | |
Molecular Function | RNA-DNA hybrid ribonuclease activity | |
Biological Process | DNA replication, removal of RNA primer |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibonuclease H
- EC number
- Short namesRNase H
Gene names
Organism names
- Organism
- Taxonomic lineageBacteria > Bdellovibrionota > Bacteriovoracia > Bacteriovoracales > Halobacteriovoraceae
Accessions
- Primary accessionA0A2E4DCD5
Proteomes
Subcellular Location
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for coiled coil, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Coiled coil | 4-31 | |||||
Sequence: SETATAALDVLREEAKQLSDAAVKEKST | ||||||
Domain | 43-188 | RNase H type-1 | ||||
Sequence: KDHAFAIYSDGACRGNPGPGSFAFIVQDSKGAILKSNAVAFEQTTNNRMELMGAIAALEEFSVSPMHELYIFTDSKYMVDGMKSWVSGWKKRGWKKADKKEPENLDLWKKLDALAASVNVSFHWVKGHSGHPQNEYVDQLANEVLD |
Sequence similarities
Belongs to the RNase H family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length192
- Mass (Da)21,248
- Last updated2018-04-25 v1
- ChecksumC3E1C1F409B5DA17