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A0A2E0KFE0 · A0A2E0KFE0_9SYNE

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.
    EC:3.2.2.31 (UniProtKB | ENZYME | Rhea)

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Features

Showing features for binding site.

140150100150200250300350400
TypeIDPosition(s)Description
Binding site2838-oxo-dGTP (UniProtKB | ChEBI)
Binding site294-2978-oxo-dGTP (UniProtKB | ChEBI)
Binding site297Mg2+ (UniProtKB | ChEBI)
Binding site317Mg2+ (UniProtKB | ChEBI)
Binding site3798-oxo-dGTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function8-oxo-7,8-dihydroguanine DNA N-glycosylase activity
Molecular Function8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
Molecular Functionadenine/guanine mispair binding
Molecular Functionmetal ion binding
Molecular Functionoxidized purine DNA binding
Molecular Functionpurine-specific mismatch base pair DNA N-glycosylase activity
Biological Processbase-excision repair
Biological Processmismatch repair

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenine DNA glycosylase
  • EC number

Gene names

    • ORF names
      CMN97_07080

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Bacteria > Cyanobacteriota > Cyanophyceae > Synechococcales > Synechococcaceae > Synechococcus

Accessions

  • Primary accession
    A0A2E0KFE0

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain261-388Nudix hydrolase

Sequence similarities

Belongs to the Nth/MutY family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    401
  • Mass (Da)
    44,481
  • Last updated
    2018-04-25 v1
  • MD5 Checksum
    5691C0BFEFA52CBECB7DDD5732AF0DAF
MPSLALGTTDLEAISADLDQALLQWWEKHGRRDPAQKPWMFMPDGAWPEPQHSLPPYGVLVAEVMLQQTQLQVVLPYWRAWMEAFPRLEVLAEADEQAVLLRWQGLGYYSRARRLLAAAQQLFAELRPVGEADPQAWPHQLDRWLLLPGIGRSTAGGILSSAFNSPLAILDGNVRRVLARVMAHSHPPMRHQGLFWTWSQCLIAAAPQRARDLNQALMDLGATLCTPRHPACASCPWQSACAAYASGSPDHYPVKEAPRDVPFQVIGVGVVLNQAGQVLIDQRLNEGLLGGMWEFPGGKQEPGELIQATIARELMEELAIEVTVDQELICVDHAYSHKRLRFEVYLCTWCSGEPQPLASQQVRWVQPQELGAYPFPAANARIIAALMTHLGLPALDQSVSG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NZXF01000037
EMBL· GenBank· DDBJ
MAS27995.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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