A0A2D3TFE5 · A0A2D3TFE5_9ENTR

Function

function

Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-2-decenoyl-ACP and then its isomerization to Z-3-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

Catalytic activity

Pathway

Lipid metabolism; fatty acid biosynthesis.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site71

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
Molecular Functiontrans-2-decenoyl-acyl-carrier-protein isomerase activity
Biological Processunsaturated fatty acid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
  • EC number
  • Alternative names
    • 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA
    • Beta-hydroxydecanoyl thioester dehydrase
    • Trans-2-decenoyl-[acyl-carrier-protein] isomerase
      (EC:5.3.3.14
      ) . EC:5.3.3.14 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      fabA
    • ORF names
      BJP41_09635
      , BJP43_09960

Organism names

  • Taxonomic identifier
  • Strains
    • A2C
    • ZA17
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > aphid secondary symbionts > Candidatus Hamiltonella

Accessions

  • Primary accession
    A0A2D3TFE5

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the thioester dehydratase family. FabA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    171
  • Mass (Da)
    18,891
  • Last updated
    2018-01-31 v1
  • Checksum
    DA1940EE6AEF74C4
MMNEYGAYSRKDLEASARGELFGPKGPRLPASNMLMIDRVITMTKDGGMHGKGYVEAELDVHPNLWFFGCHFIDDPVMPGCLGLDAMWQLVGFYLGWLENEGKGRALGVGEVKFKGQVLPDSKKITYCIDFKKVITGKLIMGIADGKVLSDGQQIYTADDLKVGLFKNTSF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP017606
EMBL· GenBank· DDBJ
ATW30542.1
EMBL· GenBank· DDBJ
Genomic DNA
CP017613
EMBL· GenBank· DDBJ
ATW34527.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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