A0A2D3T891 · A0A2D3T891_9ENTR

Function

function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site11ATP (UniProtKB | ChEBI)
Binding site59ATP (UniProtKB | ChEBI)
Binding site87ATP (UniProtKB | ChEBI)
Binding site93ATP (UniProtKB | ChEBI)
Binding site104ATP (UniProtKB | ChEBI)
Binding site114ATP (UniProtKB | ChEBI)
Active site117Pros-phosphohistidine intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionnucleoside diphosphate kinase activity
Biological ProcessCTP biosynthetic process
Biological ProcessGTP biosynthetic process
Biological Processphosphorylation
Biological ProcessUTP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Nucleoside diphosphate kinase
  • EC number
  • Short names
    NDK
    ; NDP kinase
  • Alternative names
    • Nucleoside-2-P kinase

Gene names

    • Name
      ndk
    • ORF names
      BJP41_05975
      , BJP43_06850

Organism names

  • Taxonomic identifier
  • Strains
    • A2C
    • ZA17
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > aphid secondary symbionts > Candidatus Hamiltonella

Accessions

  • Primary accession
    A0A2D3T891

Proteomes

Subcellular Location

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-140Nucleoside diphosphate kinase-like

Sequence similarities

Belongs to the NDK family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    141
  • Mass (Da)
    15,809
  • Last updated
    2018-01-31 v1
  • Checksum
    FE9E9EAAB2C4E72E
MAVERTFSIIKPKAVTKNVIGAIYTRFETAKLKIISAKMLLLTIEQAEGFYVEHKNRDFFTNLIQSITSGPVMIQVLEGENAVKRNREIMGETDPKKALAGTLRADFGDSLTDNALHGSDSLASAEREIAYFFKFDEIFSR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP017606
EMBL· GenBank· DDBJ
ATW29950.1
EMBL· GenBank· DDBJ
Genomic DNA
CP017613
EMBL· GenBank· DDBJ
ATW34021.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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