A0A2D3SZW0 · A0A2D3SZW0_9ENTR

Function

function

Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

prenyl-FMN (UniProtKB | Rhea| CHEBI:87746 )

Note: Binds 1 prenylated FMN (prenyl-FMN) per subunit.

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site171Mn2+ (UniProtKB | ChEBI)
Binding site174-176prenyl-FMN (UniProtKB | ChEBI)
Binding site188-190prenyl-FMN (UniProtKB | ChEBI)
Binding site193-194prenyl-FMN (UniProtKB | ChEBI)
Binding site237Mn2+ (UniProtKB | ChEBI)
Active site286Proton donor

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentplasma membrane
Molecular Function3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Molecular Functionmetal ion binding
Biological Processubiquinone biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-octaprenyl-4-hydroxybenzoate carboxy-lyase
  • EC number
  • Alternative names
    • Polyprenyl p-hydroxybenzoate decarboxylase

Gene names

    • Name
      ubiD
    • ORF names
      BJP41_08935

Organism names

  • Taxonomic identifier
  • Strain
    • A2C
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > aphid secondary symbionts > Candidatus Hamiltonella

Accessions

  • Primary accession
    A0A2D3SZW0

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-893-octaprenyl-4-hydroxybenzoate carboxy-lyase-like N-terminal
Domain124-3213-octaprenyl-4-hydroxybenzoate carboxy-lyase-likw Rift-related
Domain327-4513-octaprenyl-4-hydroxybenzoate carboxy-lyase-like C-terminal

Sequence similarities

Belongs to the UbiD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    495
  • Mass (Da)
    55,943
  • Last updated
    2018-01-31 v1
  • Checksum
    D9B48664B371E852
MKYKDLRDFLALLEAKGELKRIHQTIDPFLEMTEISDRTLQAQGPALLFEKPKGHAMPVLCNLFGTTQRVAMGMGQKDISTLRELGQLLAFLKEPEPPKGFRDLLSKLPKFKQILNMPNKILTSAPCQEEIWKDNLDLGCLPAMHCWPGDVAPLITWGLTITRGPHKERQNLGIYRQQVLSKNKIIMRWLPHRGGALDYREWCKTNPGQPFPVAVALGADPATILGAVTPVPDTLSEYAFSGLLRGYRTEVVKCLSSDLQVPANAEIVLEGYIQPGETAEEGPYGDHTGYYNETEHFPVFTVSHITKRQDAIYHSTYTGRPPDEPSILGAALNEVFIPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDINARNWNDVIWAITTRMDPARDTLLIENTPIDYLDFASPVAGLGSKMGLDATNKWSAETQRVWGRTIKMDKSVCDRIDAIWDELNIFNQQSVKKK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP017606
EMBL· GenBank· DDBJ
ATW30425.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help