A0A2D3RAE3 · A0A2D3RAE3_9SPHN
- ProteinPeroxisomal trans-2-enoyl-CoA reductase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids298 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Participates in chain elongation of fatty acids. Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA. Has no 2,4-dienoyl-CoA reductase activity.
Catalytic activity
- (2E)-decenoyl-CoA + NADPH + H+ = decanoyl-CoA + NADP+This reaction proceeds in the forward direction.
- (2E)-dodecenoyl-CoA + NADPH + H+ = dodecanoyl-CoA + NADP+This reaction proceeds in the forward direction.
- (2E)-hexenoyl-CoA + NADPH + H+ = hexanoyl-CoA + NADP+This reaction proceeds in the forward direction.
- (2E)-octenoyl-CoA + NADPH + H+ = octanoyl-CoA + NADP+This reaction proceeds in the forward direction.
- (2E)-tetradecenoyl-CoA + NADPH + H+ = tetradecanoyl-CoA + NADP+This reaction proceeds in the forward direction.
Pathway
Lipid metabolism.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | peroxisome | |
Molecular Function | oxidoreductase activity | |
Biological Process | fatty acid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePeroxisomal trans-2-enoyl-CoA reductase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingorhabdus
Accessions
- Primary accessionA0A2D3RAE3
Proteomes
Subcellular Location
PTM/Processing
Keywords
- PTM
Interaction
Subunit
Interacts with PEX5, probably required to target it into peroxisomes.
Structure
Sequence
- Sequence statusComplete
- Length298
- Mass (Da)32,179
- Last updated2018-01-31 v1
- MD5 Checksum1F1B7E7071EC9D59710F78A61D48B58C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP022548 EMBL· GenBank· DDBJ | ATW02259.1 EMBL· GenBank· DDBJ | Genomic DNA |