A0A2D3RAE3 · A0A2D3RAE3_9SPHN

Function

function

Participates in chain elongation of fatty acids. Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA. Has no 2,4-dienoyl-CoA reductase activity.

Catalytic activity

  • (2E)-decenoyl-CoA + NADPH + H+ = decanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-dodecenoyl-CoA + NADPH + H+ = dodecanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-hexenoyl-CoA + NADPH + H+ = hexanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-octenoyl-CoA + NADPH + H+ = octanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-tetradecenoyl-CoA + NADPH + H+ = tetradecanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • a (2E)-enoyl-CoA + NADPH + H+ = a 2,3-saturated acyl-CoA + NADP+
    This reaction proceeds in the forward direction.
    EC:1.3.1.38 (UniProtKB | ENZYME | Rhea)

Pathway

Lipid metabolism.

GO annotations

AspectTerm
Cellular Componentperoxisome
Molecular Functionoxidoreductase activity
Biological Processfatty acid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Peroxisomal trans-2-enoyl-CoA reductase
  • EC number

Gene names

    • ORF names
      CHN51_00960

Organism names

  • Taxonomic identifier
  • Strain
    • YGSMI21
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingorhabdus

Accessions

  • Primary accession
    A0A2D3RAE3

Proteomes

Subcellular Location

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Interacts with PEX5, probably required to target it into peroxisomes.

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region206-227Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    298
  • Mass (Da)
    32,179
  • Last updated
    2018-01-31 v1
  • MD5 Checksum
    1F1B7E7071EC9D59710F78A61D48B58C
MDTSKLMFRDGLMKGERILVTGGGTGLGKEMAEGLLKLGAEVHICGRRGDVCKATAEELVEKHGGKVVPHPCDIRSAEMISEMNDIIWQQHGPLTGLINNAAGNFISRTEDLSIRGFDAIANIVFRGTFYMTHDIGKRWIEGGTRGNVVSILTTWVWNGSAFTVPSAMSKAGINVMTQSLAVEWARHNIRLNAIAPGLFPTEGMSARLNPTGSDEDRKRSGAPINRPGEMHELANLATFLLGPGVEYLTGQTIAIDGGSYLASGGNFSQLLGWGDEEWNAAKDAIQGQNQKDRAKRTV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP022548
EMBL· GenBank· DDBJ
ATW02259.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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