A0A2D2M5A8 · A0A2D2M5A8_9PSED

  • Protein
    Catalase-peroxidase
  • Gene
    katG
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

TypeIDPosition(s)Description
Site93Transition state stabilizer
Active site97Proton acceptor
Binding site260Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      CS390_08830

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • HLS-6
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A2D2M5A8

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link219↔245Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-96)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-24Disordered
Domain130-422Plant heme peroxidase family profile

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    732
  • Mass (Da)
    79,188
  • Last updated
    2018-01-31 v1
  • Checksum
    DC6A724E68E62721
MSNEATCPFAGGARKHTTAGAPSNADWWPDQLNLKILHSHAPQANPLGEAFNYAEAFKSLDLDAVIKDLHALMRDSQAWWPADYGHYGPLFIRMAWHSAGTYRIADGRGGAGGGAQRFAPLNSWPDNGNLDKARRLLWPIKQKYGNSLSWADLMVLAGNVALDSMGLKTFGFGGGRVDIWEPEDDIYWGPEGKWLADERYSGDRELENPLGAVQMGLIYVNPEGPNGNPDPLAAARDIRETFARMAMNDEETVALIAGGHTFGKAHGAADPSQYVGPEPEAATLEEQGLGWKNTFGSGNGANTITSGLEGAWTTNPVKWDNNYFENLFGYEWTLTKSPAGAHQWTPKEASAAGTVPDAHDPTKTHAPIMFTTDLALIMDPVYAPISKRFHADPQALAEAFAKAWFKLTHRDMGPVSRYLGPLVPQEPLLWQDPVPAVDHPLIGEQDIATLKARLLASGLSIAQLVTTAWASAATFRGSDKRGGANGARIRLAPQKDWAVNQPAELAKVLHTLTAIQQDFNNAQAGGKNVSLADLIVLGGCAAIEAAAKRAGHEVTVPFSPGRTDASQEQTDVASFAVLEPSADGFRNYLRSGLEESAAELLLDRANQLTLSAPEMTVLIGGLRALNCNVGQVAHGVFTQRPETLTNDVFVNLLDMNTTWQRSAVTEGVLEGRDRSTGALKWTGTVVDLVFGSNAQLRAIAEVYASRDAQPLFVRHFVAAWNKVMNLDRFDLA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP024478
EMBL· GenBank· DDBJ
ATR82657.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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