A0A2D2M190 · A0A2D2M190_9PSED

  • Protein
    3-octaprenyl-4-hydroxybenzoate carboxy-lyase
  • Gene
    ubiD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

prenyl-FMN (UniProtKB | Rhea| CHEBI:87746 )

Note: Binds 1 prenylated FMN (prenyl-FMN) per subunit.

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site172Mn2+ (UniProtKB | ChEBI)
Binding site175-177prenyl-FMN (UniProtKB | ChEBI)
Binding site189-191prenyl-FMN (UniProtKB | ChEBI)
Binding site194-195prenyl-FMN (UniProtKB | ChEBI)
Binding site238Mn2+ (UniProtKB | ChEBI)
Active site287Proton donor

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Function3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Molecular Functionmetal ion binding
Biological Processubiquinone biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-octaprenyl-4-hydroxybenzoate carboxy-lyase
  • EC number
  • Alternative names
    • Polyprenyl p-hydroxybenzoate decarboxylase

Gene names

    • Name
      ubiD
    • ORF names
      CS390_01285

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • HLS-6
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A2D2M190

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain12-893-octaprenyl-4-hydroxybenzoate carboxy-lyase-like N-terminal
Domain122-3223-octaprenyl-4-hydroxybenzoate carboxy-lyase-likw Rift-related
Domain328-4523-octaprenyl-4-hydroxybenzoate carboxy-lyase-like C-terminal

Sequence similarities

Belongs to the UbiD family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    488
  • Mass (Da)
    54,737
  • Last updated
    2018-01-31 v1
  • Checksum
    05F09E081CBE8B6E
MQYRDLRDFIRGLEQRGELKRIQVPISPVLEMTEVCDRTLRAKGPALLFERPTGHDIPVLGNLFGTPERVAMGMGAESVSELREIGKLLAFLKEPEPPKGLKDAWSKLPIFKKVVSMAPKVVKDAVCQEVVIEGDDVDLGMLPVQTCWPGDVAPLITWGLTVTRGPNKDRQNLGIYRQQVIGRNKVIMRWLSHRGGALDYREWCDKNPGKPFPVAVALGADPATILGAVTPVPDTLSEYAFAGLLRGNRTELVKCRGSDLQVPASAEIILEGVIHPGEMAPEGPYGDHTGYYNEVDSFPVFTVERITHRTKPIYHSTYTGRPPDEPAILGVALNEVFVPILQKQFPEITDFYLPPEGCSYRMAVVTMKKQYPGHAKRVMLGVWSFLRQFMYTKFVIVTDDDINARDWNDVIWAITTRMDPKRDTVMIDNTPIDYLDFASPISGLGSKMGLDATHKWPGETTREWGRVIVKDEAVTRRIDELWNQLGID

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP024478
EMBL· GenBank· DDBJ
ATR81269.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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