A0A2D2LTZ8 · A0A2D2LTZ8_MOROS

  • Protein
    tRNA (cytidine(34)-2'-O)-methyltransferase
  • Gene
    trmL
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site81S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site105S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site127S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site135S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionRNA binding
Molecular FunctiontRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity
Molecular FunctiontRNA (cytidine(34)-2'-O)-methyltransferase activity
Biological Processwobble position cytosine ribose methylation
Biological Processwobble position uridine ribose methylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA (cytidine(34)-2'-O)-methyltransferase
  • EC number
  • Alternative names
    • tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL

Gene names

    • Name
      trmL
    • ORF names
      NP7_04115

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NP7
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Moraxella

Accessions

  • Primary accession
    A0A2D2LTZ8

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-147tRNA/rRNA methyltransferase SpoU type

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    174
  • Mass (Da)
    19,188
  • Last updated
    2018-01-31 v1
  • Checksum
    9D7C7B8214AF7AF2
MIHVVLVEPKMPSNTGNIIRLCANTGATLHLVEPLGFALEDKKLRRAGLDYHEWANVKVHANWQDAQDSLSQSGVQRIVALTTKLSKPLYDEDFAQLANIALVFGSETAGLPEPIRAAIGQDNWLRLPMLPTSRSLNLSNSVAITLFEVWRQQGFGGDNGHSIGYDNLVPYDPK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP024443
EMBL· GenBank· DDBJ
ATR78508.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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