A0A2D2LSQ6 · A0A2D2LSQ6_MOROS

  • Protein
    Pyridoxine 5'-phosphate synthase
  • Gene
    pdxJ
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5.

Features

Showing features for binding site, active site, site.

124920406080100120140160180200220240
TypeIDPosition(s)Description
Binding site113-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Binding site13-141-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Binding site223-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Active site47Proton acceptor
Binding site491-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Binding site541-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Active site74Proton acceptor
Binding site1041-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Site155Transition state stabilizer
Active site200Proton donor
Binding site2013-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Binding site222-2233-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionpyridoxine 5'-phosphate synthase activity
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxine 5'-phosphate synthase
  • EC number
  • Short names
    PNP synthase

Gene names

    • Name
      pdxJ
    • ORF names
      NP7_01440

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NP7
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Moraxella

Accessions

  • Primary accession
    A0A2D2LSQ6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homooctamer; tetramer of dimers.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the PNP synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    249
  • Mass (Da)
    27,011
  • Last updated
    2018-01-31 v1
  • Checksum
    BFAE238538DC2ACF
MTSNQPLLGVNIDHIATLRQARGVAYPDPVAGALICEQAGADGITLHLREDRRHIQDDDVYRLAKVITTRMNLEMAVTDEMVAIACDVKPAWVCFVPEKRQELTTEGGLDVIGNQHKIARAIQQLHQVGTQVSLFIDPELAQIDKSIALGADAIELHTGAYADYWLQQDQVKISHEITRIKTAVTHAHQAKASLLVNAGHGLTRDNVAPIASIAGIHELNIGHAIIADSVFMGLSQAVVAMRKAFTAKA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP024443
EMBL· GenBank· DDBJ
ATR78053.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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