Identify CRMP-1 as a novel regulator of actin filament elongation and reveal a surprisingly important role for CRMP-1 EVL and actin polymerization in maintaining the structural integrity of epithelial sheets.
ENA/VASP-family proteins are functionally redundant in homologous recombination and MENA VASP and EVL may be involved in the DSB repair pathway in humans
EVL protein is a novel recombination factor that may be required for repairing specific DNA lesions and that may cause tumor malignancy by its inappropriate expression.
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